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- Q6590402 subject Q7336348.
- Q6590402 abstract "Urotensin-II (U-II) is a peptide ligand, initially isolated from the neurosecretory system of the Goby fish (Gillichthys mirabilis). For many years it was thought that U-II does not exhibit significant effects in mammalian systems; a view quickly overturned when it was demonstrated that Goby U-II produces slow relaxation of mouse anococcygeus muscle, in addition to contraction of rat artery segments. In 1998, the cDNA encoding a U-II precursor was cloned in humans, unequivocally demonstrating its existence in mammalian species.The vasoconstriction it inducescan cause or exacerbate hypertension, congestiveheart failure, and coronary artery disease.In fish, U-II is secreted at the back part of the spinal cord, in a neurosecretory center called uroneurapophysa, and is involved in the regulation of the renal and cardiovascular systems. In mammals, it is involved in the regulation of the cardiovascular system.".
- Q6590402 iupacName "(L)-α-glutamyl-(L)-threonyl-(L)-prolyl-(L)-α-aspartyl-(L)-cysteinyl-(L)-phenylalanyl-(L)-tryptophyl-(L)-lysyl-(L)-tyrosyl-(L)-cysteinyl-(L)-valine (5→10)-disulfide".
- Q6590402 thumbnail Urotensin_II.svg?width=300.
- Q6590402 wikiPageWikiLink Q11068.
- Q6590402 wikiPageWikiLink Q15319948.
- Q6590402 wikiPageWikiLink Q172847.
- Q6590402 wikiPageWikiLink Q181100.
- Q6590402 wikiPageWikiLink Q193161.
- Q6590402 wikiPageWikiLink Q261485.
- Q6590402 wikiPageWikiLink Q27348.
- Q6590402 wikiPageWikiLink Q283478.
- Q6590402 wikiPageWikiLink Q3338699.
- Q6590402 wikiPageWikiLink Q369614.
- Q6590402 wikiPageWikiLink Q4468.
- Q6590402 wikiPageWikiLink Q609809.
- Q6590402 wikiPageWikiLink Q7336348.
- Q6590402 wikiPageWikiLink Q864491.
- Q6590402 arm "p".
- Q6590402 band "36".
- Q6590402 chromosome "1".
- Q6590402 entrezgene "10911".
- Q6590402 hgncid "12636".
- Q6590402 iupacname "(L)-α-glutamyl-(L)-threonyl-(L)-prolyl-(L)-α-aspartyl-(L)-cysteinyl-(L)-phenylalanyl-(L)-tryptophyl-(L)-lysyl-(L)-tyrosyl-(L)-cysteinyl-(L)-valine -disulfide".
- Q6590402 name "Urotensin-II".
- Q6590402 omim "604097".
- Q6590402 refseq "NM_021995".
- Q6590402 symbol "U-II".
- Q6590402 uniprot "O95399".
- Q6590402 type ChemicalCompound.
- Q6590402 type ChemicalSubstance.
- Q6590402 type ChemicalObject.
- Q6590402 type Thing.
- Q6590402 type Q11173.
- Q6590402 comment "Urotensin-II (U-II) is a peptide ligand, initially isolated from the neurosecretory system of the Goby fish (Gillichthys mirabilis). For many years it was thought that U-II does not exhibit significant effects in mammalian systems; a view quickly overturned when it was demonstrated that Goby U-II produces slow relaxation of mouse anococcygeus muscle, in addition to contraction of rat artery segments.".
- Q6590402 label "Urotensin-II".
- Q6590402 depiction Urotensin_II.svg.