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- Q6460424 subject Q7930599.
- Q6460424 abstract "LY-341,495 is a research drug developed by the pharmaceutical company Eli Lilly, which acts as a potent and selective orthosteric antagonist for the group II metabotropic glutamate receptors (mGluR2/3).It is used in scientific research in several different areas, showing antidepressant effects in animal models, increasing the behavioural effects of hallucinogenic drugs in animal tests, and increasing the analgesic effects of μ-opioid agonists, as well as modulating dopamine receptor function.The 1-fluorocyclopropane analog has a superior pharmacokinetic profile and similar mGluR2/3 affinity, and making a prodrug from this with the heptyl ester increases bioavailability still further.".
- Q6460424 casNumber "201943-63-7".
- Q6460424 iupacName "2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-(D)-alanine".
- Q6460424 thumbnail LY-341,495.svg?width=300.
- Q6460424 wikiPageWikiLink Q14911924.
- Q6460424 wikiPageWikiLink Q173235.
- Q6460424 wikiPageWikiLink Q2033959.
- Q6460424 wikiPageWikiLink Q323936.
- Q6460424 wikiPageWikiLink Q389934.
- Q6460424 wikiPageWikiLink Q415496.
- Q6460424 wikiPageWikiLink Q5010218.
- Q6460424 wikiPageWikiLink Q603741.
- Q6460424 wikiPageWikiLink Q632240.
- Q6460424 wikiPageWikiLink Q76560.
- Q6460424 wikiPageWikiLink Q7930599.
- Q6460424 casNumber "201943".
- Q6460424 iupacName "2".
- Q6460424 type ChemicalSubstance.
- Q6460424 type Drug.
- Q6460424 type ChemicalObject.
- Q6460424 type Thing.
- Q6460424 type Q8386.
- Q6460424 comment "LY-341,495 is a research drug developed by the pharmaceutical company Eli Lilly, which acts as a potent and selective orthosteric antagonist for the group II metabotropic glutamate receptors (mGluR2/3).It is used in scientific research in several different areas, showing antidepressant effects in animal models, increasing the behavioural effects of hallucinogenic drugs in animal tests, and increasing the analgesic effects of μ-opioid agonists, as well as modulating dopamine receptor function.The 1-fluorocyclopropane analog has a superior pharmacokinetic profile and similar mGluR2/3 affinity, and making a prodrug from this with the heptyl ester increases bioavailability still further.".
- Q6460424 label "LY-341,495".
- Q6460424 depiction LY-341,495.svg.