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- Q6459781 subject Q8744386.
- Q6459781 abstract "LR132 or (+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.1 nM for the sigma-1 receptor and more than 350 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with LR132 significantly decreases the convulsivity and lethality of cocaine.".
- Q6459781 casNumber "135211-15-3".
- Q6459781 iupacName "(+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine".
- Q6459781 thumbnail LR132.png?width=300.
- Q6459781 wikiPageWikiLink Q12744660.
- Q6459781 wikiPageWikiLink Q14907850.
- Q6459781 wikiPageWikiLink Q245204.
- Q6459781 wikiPageWikiLink Q41576.
- Q6459781 wikiPageWikiLink Q4835354.
- Q6459781 wikiPageWikiLink Q7512215.
- Q6459781 wikiPageWikiLink Q7512419.
- Q6459781 wikiPageWikiLink Q8744386.
- Q6459781 wikiPageWikiLink Q899107.
- Q6459781 casNumber "135211".
- Q6459781 iupacName "-34".
- Q6459781 type ChemicalSubstance.
- Q6459781 type Drug.
- Q6459781 type ChemicalObject.
- Q6459781 type Thing.
- Q6459781 type Q8386.
- Q6459781 comment "LR132 or (+)-3,4-dichloro-N-[(1R,2S)-2-(1-pyrrolidinyl)cyclohexyl]benzeneethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.1 nM for the sigma-1 receptor and more than 350 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with LR132 significantly decreases the convulsivity and lethality of cocaine.".
- Q6459781 label "LR132".
- Q6459781 depiction LR132.png.