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- Q6456062 subject Q8854538.
- Q6456062 abstract "L-368,899 is a drug used in scientific research which acts as a selective antagonist of the oxytocin receptor, with good selectivity over the related vasopressin receptors. Unlike related drugs such as the peripherally selective L-371,257, the oral bioavailabity is high and the brain penetration of L-368,899 is rapid, with selective accumulation in areas of the limbic system. This makes it a useful tool for investigating the centrally mediated roles of oxytocin, such as in social behaviour and pair bonding, and studies in primates have shown L-368,899 to reduce a number of behaviours such as food sharing, sexual activity and caring for infants, demonstrating the importance of oxytocinergic signalling in mediating these important social behaviours.".
- Q6456062 casNumber "148927-60-0".
- Q6456062 iupacName "(S)-2-amino-N-((1S,2S,4R)-7,7-dimethyl-1-((4-o-tolylpiperazin-1-ylsulfonyl)methyl)bicyclo[2.2.1]heptan-2-yl)-4-(methylsulfonyl)butanamide".
- Q6456062 pubchem "132857".
- Q6456062 thumbnail L-368,899_structure.png?width=300.
- Q6456062 wikiPageWikiLink Q14908140.
- Q6456062 wikiPageWikiLink Q192560.
- Q6456062 wikiPageWikiLink Q19596024.
- Q6456062 wikiPageWikiLink Q410943.
- Q6456062 wikiPageWikiLink Q421322.
- Q6456062 wikiPageWikiLink Q5382095.
- Q6456062 wikiPageWikiLink Q6456065.
- Q6456062 wikiPageWikiLink Q7316883.
- Q6456062 wikiPageWikiLink Q7916883.
- Q6456062 wikiPageWikiLink Q8854538.
- Q6456062 casNumber "148927".
- Q6456062 iupacName "-2".
- Q6456062 pubchem "132857".
- Q6456062 type ChemicalSubstance.
- Q6456062 type Drug.
- Q6456062 type ChemicalObject.
- Q6456062 type Thing.
- Q6456062 type Q8386.
- Q6456062 comment "L-368,899 is a drug used in scientific research which acts as a selective antagonist of the oxytocin receptor, with good selectivity over the related vasopressin receptors. Unlike related drugs such as the peripherally selective L-371,257, the oral bioavailabity is high and the brain penetration of L-368,899 is rapid, with selective accumulation in areas of the limbic system.".
- Q6456062 label "L-368,899".
- Q6456062 depiction L-368,899_structure.png.