Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q6385498> ?p ?o }
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- Q6385498 subject Q7145142.
- Q6385498 subject Q7215860.
- Q6385498 subject Q8418429.
- Q6385498 subject Q8878420.
- Q6385498 subject Q8887197.
- Q6385498 abstract "Kelatorphan is a drug which acts as a powerful and complete inhibitor of nearly all of the enzymes responsible for catabolism of the endogenous enkephalins, including neutral endopeptidase (NEP), dipeptidyl peptidase III (DPP3), aminopeptidase N (APN), and angiotensin-converting enzyme (ACE). In mice, with the intracerebroventricular co-administration of a 50 µg dose of kelatorphan (this route is necessary because kelatorphan is incapable of crossing the blood-brain-barrier) hence alongside exogenous [Met]enkephalin (ED50 approximately 10 ng), it potentiated the analgesic effects of the latter by 50,000 times. Kelatorphan also displays potent antinociceptive effects alone, and does not depress respiration, although at high doses it actually increases it.".
- Q6385498 atcPrefix "None".
- Q6385498 casNumber "92175-57-0".
- Q6385498 drugbank "DB08040".
- Q6385498 iupacName "N-[(2R)-2-benzyl-4-(hydroxyamino)-4-oxobutanoyl]-(L)-alanine".
- Q6385498 pubchem "123982".
- Q6385498 thumbnail Kelatorphan.svg?width=300.
- Q6385498 wikiPageWikiLink Q1378064.
- Q6385498 wikiPageWikiLink Q14863991.
- Q6385498 wikiPageWikiLink Q14864886.
- Q6385498 wikiPageWikiLink Q14911850.
- Q6385498 wikiPageWikiLink Q173235.
- Q6385498 wikiPageWikiLink Q18035003.
- Q6385498 wikiPageWikiLink Q190057.
- Q6385498 wikiPageWikiLink Q1960495.
- Q6385498 wikiPageWikiLink Q2066956.
- Q6385498 wikiPageWikiLink Q218642.
- Q6385498 wikiPageWikiLink Q221694.
- Q6385498 wikiPageWikiLink Q2734305.
- Q6385498 wikiPageWikiLink Q285982.
- Q6385498 wikiPageWikiLink Q293000.
- Q6385498 wikiPageWikiLink Q325101.
- Q6385498 wikiPageWikiLink Q427492.
- Q6385498 wikiPageWikiLink Q5379025.
- Q6385498 wikiPageWikiLink Q7145142.
- Q6385498 wikiPageWikiLink Q7215860.
- Q6385498 wikiPageWikiLink Q8047.
- Q6385498 wikiPageWikiLink Q8386.
- Q6385498 wikiPageWikiLink Q8418429.
- Q6385498 wikiPageWikiLink Q8878420.
- Q6385498 wikiPageWikiLink Q8887197.
- Q6385498 wikiPageWikiLink Q912751.
- Q6385498 atcPrefix "None".
- Q6385498 casNumber "92175".
- Q6385498 drugbank "DB08040".
- Q6385498 iupacName "N-[-2-benzyl-4--4-oxobutanoyl]-(L)-alanine".
- Q6385498 pubchem "123982".
- Q6385498 type ChemicalSubstance.
- Q6385498 type Drug.
- Q6385498 type ChemicalObject.
- Q6385498 type Thing.
- Q6385498 type Q8386.
- Q6385498 comment "Kelatorphan is a drug which acts as a powerful and complete inhibitor of nearly all of the enzymes responsible for catabolism of the endogenous enkephalins, including neutral endopeptidase (NEP), dipeptidyl peptidase III (DPP3), aminopeptidase N (APN), and angiotensin-converting enzyme (ACE).".
- Q6385498 label "Kelatorphan".
- Q6385498 depiction Kelatorphan.svg.