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- Q612108 subject Q18057279.
- Q612108 abstract "Acute promyelocytic leukemia (APML, APL) is the M3 subtype of acute myelogenous leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARα or RARA) gene and is distinguished from other forms of AML by its responsiveness to all-trans retinoic acid (ATRA; also known as tretinoin) therapy. Acute promyelocytic leukemia was first characterized in 1957 by French and Norwegian physicians as a hyperacute fatal illness. Currently it is one of the most treatable forms of leukemia with a 12-year progression-free survival rate that is estimated to be approximately 70%.".
- Q612108 icd10 "C92.4".
- Q612108 icd9 "205.0".
- Q612108 meshId "D015473".
- Q612108 omim "102578".
- Q612108 thumbnail Neutrophilic_promyelocyte.png?width=300.
- Q612108 wikiPageExternalLink 1875.
- Q612108 wikiPageExternalLink SECTION00414000000000000000.
- Q612108 wikiPageExternalLink myeloid1.cfm.
- Q612108 wikiPageExternalLink ?report=printable.
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- Q612108 wikiPageWikiLink Q18057279.
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- Q612108 icd "205".
- Q612108 icd "92.4".
- Q612108 meshid "D015473".
- Q612108 name "Acute promyelocytic leukemia".
- Q612108 omim "102578".
- Q612108 type Disease.
- Q612108 type Thing.
- Q612108 type Q12136.
- Q612108 comment "Acute promyelocytic leukemia (APML, APL) is the M3 subtype of acute myelogenous leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARα or RARA) gene and is distinguished from other forms of AML by its responsiveness to all-trans retinoic acid (ATRA; also known as tretinoin) therapy.".
- Q612108 label "Acute promyelocytic leukemia".
- Q612108 depiction Neutrophilic_promyelocyte.png.
- Q612108 name "Acute promyelocytic leukemia".