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- Q6062283 subject Q7400695.
- Q6062283 subject Q8579838.
- Q6062283 abstract "Iodolactonization (or, more generally, Halolactonization) is an organic reaction that forms a ring (the lactone) by the addition of an oxygen and iodine across a carbon-carbon double bond. The reaction was first reported by M. J. Bougalt in 1904 and has since become one of the most effective ways to synthesize lactones. Strengths of the reaction include the mild conditions and incorporation of the versatile iodine atom into the product.Iodolactonization has been used in the synthesis of many natural products including those with medicinal applications such as vernoplepin and vernomenin, two compounds used in tumor growth inhibition, and vibralactone, a pancreatic lipase inhibitor that has been used in the treatment of obesity. Iodolactonization has also been used by E.J. Corey to synthesize numerous prostaglandins.".
- Q6062283 thumbnail IodolactonizationIntroduction.svg?width=300.
- Q6062283 wikiPageWikiLink Q104116.
- Q6062283 wikiPageWikiLink Q11367.
- Q6062283 wikiPageWikiLink Q11473.
- Q6062283 wikiPageWikiLink Q134856.
- Q6062283 wikiPageWikiLink Q135171.
- Q6062283 wikiPageWikiLink Q14865261.
- Q6062283 wikiPageWikiLink Q156.
- Q6062283 wikiPageWikiLink Q170409.
- Q6062283 wikiPageWikiLink Q209717.
- Q6062283 wikiPageWikiLink Q2275927.
- Q6062283 wikiPageWikiLink Q2469857.
- Q6062283 wikiPageWikiLink Q251124.
- Q6062283 wikiPageWikiLink Q36496.
- Q6062283 wikiPageWikiLink Q5643431.
- Q6062283 wikiPageWikiLink Q59078.
- Q6062283 wikiPageWikiLink Q644785.
- Q6062283 wikiPageWikiLink Q724239.
- Q6062283 wikiPageWikiLink Q7400695.
- Q6062283 wikiPageWikiLink Q745930.
- Q6062283 wikiPageWikiLink Q804856.
- Q6062283 wikiPageWikiLink Q81406.
- Q6062283 wikiPageWikiLink Q8579838.
- Q6062283 wikiPageWikiLink Q901227.
- Q6062283 wikiPageWikiLink Q908086.
- Q6062283 wikiPageWikiLink Q9296153.
- Q6062283 comment "Iodolactonization (or, more generally, Halolactonization) is an organic reaction that forms a ring (the lactone) by the addition of an oxygen and iodine across a carbon-carbon double bond. The reaction was first reported by M. J. Bougalt in 1904 and has since become one of the most effective ways to synthesize lactones.".
- Q6062283 label "Iodolactonization".
- Q6062283 depiction IodolactonizationIntroduction.svg.