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- Q6045608 subject Q7321094.
- Q6045608 abstract "Intercalated discs are microscopic identifying features of cardiac muscle. Cardiac muscle consists of individual heart muscle cells (cardiomyocytes) connected by intercalated discs to work as a single functional organ or syncytium. By contrast, skeletal muscle consists of multinucleated muscle fibers and exhibit no intercalated discs. Intercalated discs support synchronised contraction of cardiac tissue. They occur at the Z line of the sarcomere and can be visualized easily when observing a longitudinal section of the tissue.Three types of cell junction make up an intercalated disc — fascia adherens, desmosomes and gap junctions. Fascia adherens are anchoring sites for actin, and connect to the closest sarcomere. Desmosomes stop separation during contraction by binding intermediate filaments, joining the cells together. Desmosomes are also known as macula adherens. Gap junctions allow action potentials to spread between cardiac cells by permitting the passage of ions between cells, producing depolarization of the heart muscle.Molecular, biological, and comprehensive studies have shown that intercalated discs consist for the most part of mixed type adherens junctions, termed composite junctions or areae compositae (singular area composita). These represent an amalgamation of typical desmosomal and fascia adherens proteins (in contrast to various epithelia). Thus cardiomyocyte adherens junctions differ from epithelial adherens junctions and desmosomes.".
- Q6045608 thumbnail Glanzstreifen.jpg?width=300.
- Q6045608 wikiPageWikiLink Q1047227.
- Q6045608 wikiPageWikiLink Q1337087.
- Q6045608 wikiPageWikiLink Q185269.
- Q6045608 wikiPageWikiLink Q189073.
- Q6045608 wikiPageWikiLink Q194277.
- Q6045608 wikiPageWikiLink Q232438.
- Q6045608 wikiPageWikiLink Q421987.
- Q6045608 wikiPageWikiLink Q45173.
- Q6045608 wikiPageWikiLink Q5436623.
- Q6045608 wikiPageWikiLink Q7321094.
- Q6045608 wikiPageWikiLink Q83183.
- Q6045608 wikiPageWikiLink Q84133.
- Q6045608 wikiPageWikiLink Q844460.
- Q6045608 wikiPageWikiLink Q846957.
- Q6045608 name "Intercalated disc".
- Q6045608 type AnatomicalStructure.
- Q6045608 type Thing.
- Q6045608 type Q4936952.
- Q6045608 comment "Intercalated discs are microscopic identifying features of cardiac muscle. Cardiac muscle consists of individual heart muscle cells (cardiomyocytes) connected by intercalated discs to work as a single functional organ or syncytium. By contrast, skeletal muscle consists of multinucleated muscle fibers and exhibit no intercalated discs. Intercalated discs support synchronised contraction of cardiac tissue.".
- Q6045608 label "Intercalated disc".
- Q6045608 depiction Glanzstreifen.jpg.
- Q6045608 name "Intercalated disc".