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- Q5984942 subject Q7334131.
- Q5984942 subject Q8501361.
- Q5984942 subject Q8522216.
- Q5984942 subject Q8546974.
- Q5984942 subject Q9785517.
- Q5984942 abstract "Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191) is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. It also alters metabolism of body fat and so may have application in the treatment of obesity.".
- Q5984942 atcPrefix "None".
- Q5984942 casNumber "159634-47-6".
- Q5984942 casSupplemental "159752-10-0 (mesylate salt)".
- Q5984942 fdaUniiCode "GJ0EGN38UL".
- Q5984942 iupacName "(R)-1'-(2-methylalanyl-O-benzyl-(D)-seryl)-1-(methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine]".
- Q5984942 pubchem "9939050".
- Q5984942 thumbnail Ibutamoren_skeletal.svg?width=300.
- Q5984942 wikiPageWikiLink Q11364.
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- Q5984942 wikiPageWikiLink Q7334131.
- Q5984942 wikiPageWikiLink Q7391026.
- Q5984942 wikiPageWikiLink Q7673066.
- Q5984942 wikiPageWikiLink Q824258.
- Q5984942 wikiPageWikiLink Q8501361.
- Q5984942 wikiPageWikiLink Q8522216.
- Q5984942 wikiPageWikiLink Q8546974.
- Q5984942 wikiPageWikiLink Q9785517.
- Q5984942 atcPrefix "None".
- Q5984942 casNumber "159634".
- Q5984942 casSupplemental "159752".
- Q5984942 iupacName "-1".
- Q5984942 pubchem "9939050".
- Q5984942 unii "GJ0EGN38UL".
- Q5984942 type ChemicalSubstance.
- Q5984942 type Drug.
- Q5984942 type ChemicalObject.
- Q5984942 type Thing.
- Q5984942 type Q8386.
- Q5984942 comment "Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191) is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin.".
- Q5984942 label "Ibutamoren".
- Q5984942 depiction Ibutamoren_skeletal.svg.