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- Q5883653 subject Q6584894.
- Q5883653 abstract "First identified by Gordon Holmes in 1904, Holmes tremor can be described as a wing-beating movement localized in the upper body that is caused by cerebellar damage. Holmes tremor is a combination of rest, action, and postural tremors. Tremor frequency ranges from 2 to 5 Hertz and is aggravated with posture and movement. It may arise from various underlying structural disorders including stroke, tumors, trauma, and other cerebellar lesions. Because Holmes tremor is rare, much of the research is based on individual cases.The formation of tremors is due to two main factors: the over-excited rhythmic movement of neuronal loops and permanent structural changes from neurodegeneration. Two major neuronal networks, the corticostriatothalamocortical hap and the inferior olivary nucleus (ION) specifically target the development of the tremors. When diagnosing a patient with Holmes tremor, one must look at the neurological signs and symptoms, as well as the possibility that the tremor is caused by medications or other stimulants. In most cases, the patient’s history and a targeted neurological examination is enough to give a diagnosis.Treatment for Holmes tremor is dependent on the characteristics of the tremor. Because the disease is involved with the dopaminergic system, most treatments involve levodopa. Drugs used to treat other types of tremors are applicable to the treatment of Holmes tremor; however, these drugs have a low success rate.".
- Q5883653 wikiPageExternalLink hyperexcitability.
- Q5883653 wikiPageWikiLink Q1135939.
- Q5883653 wikiPageWikiLink Q128406.
- Q5883653 wikiPageWikiLink Q1553841.
- Q5883653 wikiPageWikiLink Q161238.
- Q5883653 wikiPageWikiLink Q16399.
- Q5883653 wikiPageWikiLink Q16499.
- Q5883653 wikiPageWikiLink Q170304.
- Q5883653 wikiPageWikiLink Q1751717.
- Q5883653 wikiPageWikiLink Q1755122.
- Q5883653 wikiPageWikiLink Q1759895.
- Q5883653 wikiPageWikiLink Q184215.
- Q5883653 wikiPageWikiLink Q2004185.
- Q5883653 wikiPageWikiLink Q208144.
- Q5883653 wikiPageWikiLink Q211036.
- Q5883653 wikiPageWikiLink Q211544.
- Q5883653 wikiPageWikiLink Q223907.
- Q5883653 wikiPageWikiLink Q271993.
- Q5883653 wikiPageWikiLink Q300989.
- Q5883653 wikiPageWikiLink Q43283.
- Q5883653 wikiPageWikiLink Q4955837.
- Q5883653 wikiPageWikiLink Q5620438.
- Q5883653 wikiPageWikiLink Q6584894.
- Q5883653 wikiPageWikiLink Q6841128.
- Q5883653 wikiPageWikiLink Q753278.
- Q5883653 wikiPageWikiLink Q76560.
- Q5883653 wikiPageWikiLink Q827023.
- Q5883653 wikiPageWikiLink Q852461.
- Q5883653 comment "First identified by Gordon Holmes in 1904, Holmes tremor can be described as a wing-beating movement localized in the upper body that is caused by cerebellar damage. Holmes tremor is a combination of rest, action, and postural tremors. Tremor frequency ranges from 2 to 5 Hertz and is aggravated with posture and movement. It may arise from various underlying structural disorders including stroke, tumors, trauma, and other cerebellar lesions.".
- Q5883653 label "Holmes tremor".