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- Q5786759 subject Q7193252.
- Q5786759 abstract "Lupus anticoagulant (also known as lupus antibody, LA, LAC, or lupus inhibitors) is an immunoglobulin that binds to phospholipids and proteins associated with the cell membrane. Lupus anticoagulant is a misnomer, as it is actually a prothrombotic agent. Lupus anticoagulant antibodies in living systems cause an increase in inappropriate blood clotting. The name derives from their properties in vitro, since in laboratory tests, these antibodies increase aPTT. Investigators speculate that the antibodies interfere with phospholipids used to induce in vitro coagulation. In vivo, the antibodies are thought to interact with platelet membrane phospholipids, increasing adhesion and aggregation of platelets, which accounts for the in vivo prothrombotic characteristics.The condition was first described by hematologist C. Lockard Conley.".
- Q5786759 icd9 "289.81".
- Q5786759 meshId "D016682".
- Q5786759 omim "107320".
- Q5786759 wikiPageWikiLink Q141124.
- Q5786759 wikiPageWikiLink Q15297019.
- Q5786759 wikiPageWikiLink Q1755136.
- Q5786759 wikiPageWikiLink Q179217.
- Q5786759 wikiPageWikiLink Q18386957.
- Q5786759 wikiPageWikiLink Q186915.
- Q5786759 wikiPageWikiLink Q188297.
- Q5786759 wikiPageWikiLink Q215118.
- Q5786759 wikiPageWikiLink Q221681.
- Q5786759 wikiPageWikiLink Q261327.
- Q5786759 wikiPageWikiLink Q2750727.
- Q5786759 wikiPageWikiLink Q407431.
- Q5786759 wikiPageWikiLink Q502159.
- Q5786759 wikiPageWikiLink Q5277080.
- Q5786759 wikiPageWikiLink Q582207.
- Q5786759 wikiPageWikiLink Q6884081.
- Q5786759 wikiPageWikiLink Q7193252.
- Q5786759 wikiPageWikiLink Q79460.
- Q5786759 wikiPageWikiLink Q8054.
- Q5786759 icd "289.81".
- Q5786759 meshid "D016682".
- Q5786759 name "Lupus anticoagulant".
- Q5786759 omim "107320".
- Q5786759 type Disease.
- Q5786759 type Thing.
- Q5786759 type Q12136.
- Q5786759 comment "Lupus anticoagulant (also known as lupus antibody, LA, LAC, or lupus inhibitors) is an immunoglobulin that binds to phospholipids and proteins associated with the cell membrane. Lupus anticoagulant is a misnomer, as it is actually a prothrombotic agent. Lupus anticoagulant antibodies in living systems cause an increase in inappropriate blood clotting. The name derives from their properties in vitro, since in laboratory tests, these antibodies increase aPTT.".
- Q5786759 label "Lupus anticoagulant".
- Q5786759 name "Lupus anticoagulant".