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- Q5629406 subject Q8680982.
- Q5629406 abstract "HNH Endonuclease-Associated RNA and ORF (HEARO) RNAs conform to a conserved RNA structure that was identified in bacteria by bioinformatics. HEARO RNAs average roughly 300 nucleotides, which is comparable to the size of many ribozymes, which catalyze chemical reactions.Multiple lines of non-experimental evidence suggest that HEARO RNAs form part of a mobile genetic element. HEARO RNAs contain an open reading frame (ORF) that usually codes for a protein containing an HNH endonuclease domain. Members of this family of endonucleases are often used by mobile genetic elements, such as group I and group II introns, to facilitate their replication. Several instances were detected of homologous sequences where only one sequence contains the HEARO element, suggesting that the HEARO element might have integrated into an ancestor of this sequence. Such cases also suggest that HEARO elements integrate 5' to ATGA or GTGA sequences, although no other integration requirements were elucidated. Additional analysis was consistent with the hypothesis of self replication.The Rfam model of HEARO RNAs uses only the region that is 5' to the ORF. This region includes the bulk of the structure, but does not include a hairpin located 3' to the ORF.".
- Q5629406 wikiPageWikiLink Q10876.
- Q5629406 wikiPageWikiLink Q11053.
- Q5629406 wikiPageWikiLink Q128570.
- Q5629406 wikiPageWikiLink Q205858.
- Q5629406 wikiPageWikiLink Q2347362.
- Q5629406 wikiPageWikiLink Q3577126.
- Q5629406 wikiPageWikiLink Q415601.
- Q5629406 wikiPageWikiLink Q5611160.
- Q5629406 wikiPageWikiLink Q5611164.
- Q5629406 wikiPageWikiLink Q8054.
- Q5629406 wikiPageWikiLink Q82264.
- Q5629406 wikiPageWikiLink Q8680982.
- Q5629406 wikiPageWikiLink Q908550.
- Q5629406 comment "HNH Endonuclease-Associated RNA and ORF (HEARO) RNAs conform to a conserved RNA structure that was identified in bacteria by bioinformatics. HEARO RNAs average roughly 300 nucleotides, which is comparable to the size of many ribozymes, which catalyze chemical reactions.Multiple lines of non-experimental evidence suggest that HEARO RNAs form part of a mobile genetic element. HEARO RNAs contain an open reading frame (ORF) that usually codes for a protein containing an HNH endonuclease domain.".
- Q5629406 label "HEARO RNA motif".