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- Q5628903 subject Q7060928.
- Q5628903 abstract "HAIR-AN syndrome consists of hyperandrogenism (HA), insulin resistance (IR), and acanthosis nigricans (AN).Although it is a rare subset of polycystic ovary syndrome, studies on patients with HAIR-AN played a key role in elucidating the pathogenesis of the former. In particular, although HAIR-AN results from two very different types of abnormalities - blocking antibodies against the insulin receptor OR genetically absent/reduced insulin receptor number/function - patients with both types have high levels of androgens (male hormones). Research on the two types of HAIR-AN demonstrated that patients with both forms of HAIR-AN had very high levels of insulin and, critically, that it was the high insulin that caused the elevation in androgens. In other words, regardless of how it comes about, high levels of insulin lead to high levels of androgens. This insight had important implications for the understanding of the more common form of polycystic ovarian syndrome and ultimately led to new treatments for it, such as metformin.".
- Q5628903 wikiPageWikiLink Q10529545.
- Q5628903 wikiPageWikiLink Q1053470.
- Q5628903 wikiPageWikiLink Q19484.
- Q5628903 wikiPageWikiLink Q246809.
- Q5628903 wikiPageWikiLink Q415833.
- Q5628903 wikiPageWikiLink Q500816.
- Q5628903 wikiPageWikiLink Q62614.
- Q5628903 wikiPageWikiLink Q7060928.
- Q5628903 wikiPageWikiLink Q7388564.
- Q5628903 wikiPageWikiLink Q949302.
- Q5628903 type Disease.
- Q5628903 type Thing.
- Q5628903 type Q12136.
- Q5628903 comment "HAIR-AN syndrome consists of hyperandrogenism (HA), insulin resistance (IR), and acanthosis nigricans (AN).Although it is a rare subset of polycystic ovary syndrome, studies on patients with HAIR-AN played a key role in elucidating the pathogenesis of the former.".
- Q5628903 label "HAIR-AN syndrome".