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- Q5521314 subject Q7214758.
- Q5521314 subject Q8493060.
- Q5521314 abstract "Ganirelix acetate (or diacetate) is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Ganirelix is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilisation.GnRH agonists are also sometimes used in reproductive therapy, as well as to treat disorders involving sex-steroid hormones, such as endometriosis. One advantage of using GnRH antagonists is that repeated administration of GnRH agonists results in decreased levels of gonadotropins and sex steroids due to desensitization of the pituitary. This is avoided when using GnRH antagonists such as Ganirelix. The success of Ganirelix in reproductive therapy has been shown to be comparable to that when using GnRH agonists.Ganirelix is derived from GnRH itself, with amino acid substitutions made at positions 1, 2, 3, 6, 8, and 10.The European Commission gave marketing authorization for Ganirelix throughout the European Union to N.V. Organon in May 2000. Ganirelix is marketed by Organon International as Antagon.".
- Q5521314 atcPrefix "H01".
- Q5521314 atcSuffix "CC01".
- Q5521314 bioavailability "91.1".
- Q5521314 casNumber "129311-55-3".
- Q5521314 drugbank "DB06785".
- Q5521314 fdaUniiCode "IX503L9WN0".
- Q5521314 iupacName "(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-[bis(ethylamino)methylideneamino]hexanoyl]amino]-4-methylpentanoyl]amino]-6-[bis(ethylamino)methylideneamino]hexanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide".
- Q5521314 pubchem "16186319".
- Q5521314 thumbnail Ganirelix.svg?width=300.
- Q5521314 wikiPageWikiLink Q14864006.
- Q5521314 wikiPageWikiLink Q187082.
- Q5521314 wikiPageWikiLink Q200117.
- Q5521314 wikiPageWikiLink Q200774.
- Q5521314 wikiPageWikiLink Q2035485.
- Q5521314 wikiPageWikiLink Q205764.
- Q5521314 wikiPageWikiLink Q208360.
- Q5521314 wikiPageWikiLink Q3244305.
- Q5521314 wikiPageWikiLink Q3606696.
- Q5521314 wikiPageWikiLink Q3618379.
- Q5521314 wikiPageWikiLink Q3869873.
- Q5521314 wikiPageWikiLink Q407172.
- Q5521314 wikiPageWikiLink Q496.
- Q5521314 wikiPageWikiLink Q5065704.
- Q5521314 wikiPageWikiLink Q7113249.
- Q5521314 wikiPageWikiLink Q7214758.
- Q5521314 wikiPageWikiLink Q7314318.
- Q5521314 wikiPageWikiLink Q8493060.
- Q5521314 wikiPageWikiLink Q903372.
- Q5521314 wikiPageWikiLink Q9377.
- Q5521314 atcPrefix "H01".
- Q5521314 atcSuffix "CC01".
- Q5521314 bioavailability "91.1".
- Q5521314 casNumber "129311".
- Q5521314 drugbank "DB06785".
- Q5521314 iupacName "-1".
- Q5521314 pubchem "16186319".
- Q5521314 unii "IX503L9WN0".
- Q5521314 type ChemicalSubstance.
- Q5521314 type Drug.
- Q5521314 type ChemicalObject.
- Q5521314 type Thing.
- Q5521314 type Q8386.
- Q5521314 comment "Ganirelix acetate (or diacetate) is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH.".
- Q5521314 label "Ganirelix".
- Q5521314 depiction Ganirelix.svg.