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- Q5520257 subject Q18924463.
- Q5520257 subject Q7215860.
- Q5520257 subject Q7441579.
- Q5520257 subject Q8479056.
- Q5520257 subject Q8529536.
- Q5520257 subject Q8672800.
- Q5520257 subject Q8788974.
- Q5520257 abstract "Gamma-Amino-beta-hydroxybutyric acid γ-Amino-β-hydroxybutyric acid (GABOB) (brand names Gamibetal, Gabomade, Aminoxan, Bogil, Diastal, Gabimex, Gaboril, Kolpo), or β-hydroxy-γ-aminobutyric acid (β-hydroxy-GABA), is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico. It is also an endogenous active metabolite and analogue of the neurotransmitter γ-aminobutyric acid (GABA), and for this reason, may function as a neurotransmitter itself. Relative to GABA, GABOB has more potent inhibitory effects on the central nervous system, perhaps due to its greater capacity to cross the blood-brain-barrier. However, GABOB is of relatively low potency as an anticonvulsant when used by itself, and is more useful as an adjuvant treatment used alongside another anticonvulsant. GABOB has two stereoisomers, with the (3S) isomer d-GABOB being around twice as potent an anticonvulsant as the (3R) isomer l-GABOB.GABOB (β-hydroxy-GABA) is a close structural analogue of GABA (see GABA analogue), as well as of γ-hydroxybutyric acid (GHB), phenibut (β-phenyl-GABA), baclofen (β-(4-chlorophenyl)-GABA), and pregabalin (β-isobutyl-GABA).".
- Q5520257 casNumber "352-21-6".
- Q5520257 iupacName "4-amino-3-hydroxybutanoic acid".
- Q5520257 pubchem "2149".
- Q5520257 thumbnail GABOB.png?width=300.
- Q5520257 wikiPageWikiLink Q162657.
- Q5520257 wikiPageWikiLink Q17.
- Q5520257 wikiPageWikiLink Q18924463.
- Q5520257 wikiPageWikiLink Q207920.
- Q5520257 wikiPageWikiLink Q210021.
- Q5520257 wikiPageWikiLink Q221694.
- Q5520257 wikiPageWikiLink Q235816.
- Q5520257 wikiPageWikiLink Q285982.
- Q5520257 wikiPageWikiLink Q357896.
- Q5520257 wikiPageWikiLink Q412174.
- Q5520257 wikiPageWikiLink Q413717.
- Q5520257 wikiPageWikiLink Q41571.
- Q5520257 wikiPageWikiLink Q419559.
- Q5520257 wikiPageWikiLink Q46.
- Q5520257 wikiPageWikiLink Q4677569.
- Q5520257 wikiPageWikiLink Q47273.
- Q5520257 wikiPageWikiLink Q485014.
- Q5520257 wikiPageWikiLink Q576618.
- Q5520257 wikiPageWikiLink Q7215860.
- Q5520257 wikiPageWikiLink Q7441579.
- Q5520257 wikiPageWikiLink Q8479056.
- Q5520257 wikiPageWikiLink Q8529536.
- Q5520257 wikiPageWikiLink Q8672800.
- Q5520257 wikiPageWikiLink Q8788974.
- Q5520257 wikiPageWikiLink Q96.
- Q5520257 casNumber "352".
- Q5520257 drugName "gamma-Amino-beta-hydroxybutyric acid".
- Q5520257 iupacName "4".
- Q5520257 pubchem "2149".
- Q5520257 type ChemicalSubstance.
- Q5520257 type Drug.
- Q5520257 type ChemicalObject.
- Q5520257 type Thing.
- Q5520257 type Q8386.
- Q5520257 comment "Gamma-Amino-beta-hydroxybutyric acid γ-Amino-β-hydroxybutyric acid (GABOB) (brand names Gamibetal, Gabomade, Aminoxan, Bogil, Diastal, Gabimex, Gaboril, Kolpo), or β-hydroxy-γ-aminobutyric acid (β-hydroxy-GABA), is an anticonvulsant which is used for the treatment of epilepsy in Europe, Japan, and Mexico. It is also an endogenous active metabolite and analogue of the neurotransmitter γ-aminobutyric acid (GABA), and for this reason, may function as a neurotransmitter itself.".
- Q5520257 label "Gamma-Amino-beta-hydroxybutyric acid".
- Q5520257 depiction GABOB.png.
- Q5520257 name "gamma-Amino-beta-hydroxybutyric acid".