Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q5426016> ?p ?o }
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- Q5426016 subject Q8395845.
- Q5426016 abstract "FK506 binding protein 6, also known as FKBP6, is a human gene. The encoded protein shows structural homology to FKBP immunophilins, which bind to the immunosuppressants FK506 and rapamycin.FKBP6 is essential for homologous chromosome pairing in meiosis during spermatogenesis. Targeted inactivation of FKBP6 in mice results in infertile males, but apparently normal females. Rats with spermatogenic failure at meiosis were found to have a deletion in the exon 8 portion of the FKBP6 gene. Mutations in this gene have been associated with male infertility in humans.FKBP6 is deleted in Williams syndrome, however this hemizygous loss of FKBP6 is not associated with infertility.FKBP6 contains 3 α-helices and 11 β-sheet strands, and as a FK506-family protein, has been shown to be a potent immunosuppressant which can assist in the prevention of allograft rejections.".
- Q5426016 arm "q".
- Q5426016 band "11.23".
- Q5426016 chromosome "7".
- Q5426016 entrezgene "8468".
- Q5426016 hgncid "3722".
- Q5426016 omim "604839".
- Q5426016 pdb "3B7X".
- Q5426016 refseq "NM_003602".
- Q5426016 symbol "FKBP36; MGC87179".
- Q5426016 symbol "FKBP6".
- Q5426016 thumbnail 3B7X.pdb.jpg?width=300.
- Q5426016 uniprot "O75344".
- Q5426016 wikiPageWikiLink Q116672.
- Q5426016 wikiPageWikiLink Q162925.
- Q5426016 wikiPageWikiLink Q32089.
- Q5426016 wikiPageWikiLink Q411648.
- Q5426016 wikiPageWikiLink Q558077.
- Q5426016 wikiPageWikiLink Q583864.
- Q5426016 wikiPageWikiLink Q7187.
- Q5426016 wikiPageWikiLink Q8054.
- Q5426016 wikiPageWikiLink Q8395845.
- Q5426016 altsymbols "FKBP36; MGC87179".
- Q5426016 arm "q".
- Q5426016 band "11.23".
- Q5426016 chromosome "7".
- Q5426016 entrezgene "8468".
- Q5426016 hgncid "3722".
- Q5426016 name "FKBP6".
- Q5426016 omim "604839".
- Q5426016 pdb "3".
- Q5426016 refseq "NM_003602".
- Q5426016 symbol "FKBP6".
- Q5426016 uniprot "O75344".
- Q5426016 type Biomolecule.
- Q5426016 type Protein.
- Q5426016 type Thing.
- Q5426016 type Q206229.
- Q5426016 type Q8054.
- Q5426016 comment "FK506 binding protein 6, also known as FKBP6, is a human gene. The encoded protein shows structural homology to FKBP immunophilins, which bind to the immunosuppressants FK506 and rapamycin.FKBP6 is essential for homologous chromosome pairing in meiosis during spermatogenesis. Targeted inactivation of FKBP6 in mice results in infertile males, but apparently normal females. Rats with spermatogenic failure at meiosis were found to have a deletion in the exon 8 portion of the FKBP6 gene.".
- Q5426016 label "FKBP6".
- Q5426016 depiction 3B7X.pdb.jpg.
- Q5426016 name "FKBP6".