Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q5119890> ?p ?o }
Showing triples 1 to 35 of
35
with 100 triples per page.
- Q5119890 subject Q6973183.
- Q5119890 subject Q8965786.
- Q5119890 abstract "Ciglitazone (INN) is a thiazolidinedione. Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones. Several analogues were later developed, some of which—such as pioglitazone and troglitazone—made it to the market.Ciglitazone significantly decreases VEGF production by human granulosa cells in an in vitro study, and may potentially be used in ovarian hyperstimulation syndrome.Ciglitazone is a potent and selective PPARγ ligand. It binds to the PPARγ ligand-binding domain with an EC50 of 3.0 µM. Ciglitazone is active in vivo as an anti-hyperglycemic agent in the ob/ob murine model. Inhibits HUVEC differentiation and angiogenesis and also stimulates adipogenesis and decreases osteoblastogenesis in human mesenchymal stem cells.".
- Q5119890 atcPrefix "none".
- Q5119890 casNumber "74772-77-3".
- Q5119890 fdaUniiCode "U8QXS1WU8G".
- Q5119890 iupacName "5-{4-[(1-methylcyclohexyl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione".
- Q5119890 pubchem "2750".
- Q5119890 thumbnail Ciglitazone.svg?width=300.
- Q5119890 wikiPageWikiLink Q1393556.
- Q5119890 wikiPageWikiLink Q1543282.
- Q5119890 wikiPageWikiLink Q1760461.
- Q5119890 wikiPageWikiLink Q286136.
- Q5119890 wikiPageWikiLink Q29725.
- Q5119890 wikiPageWikiLink Q417765.
- Q5119890 wikiPageWikiLink Q485014.
- Q5119890 wikiPageWikiLink Q5939177.
- Q5119890 wikiPageWikiLink Q6973183.
- Q5119890 wikiPageWikiLink Q7844989.
- Q5119890 wikiPageWikiLink Q824258.
- Q5119890 wikiPageWikiLink Q8965786.
- Q5119890 wikiPageWikiLink Q899133.
- Q5119890 atcPrefix "none".
- Q5119890 casNumber "74772".
- Q5119890 iupacName "5".
- Q5119890 pubchem "2750".
- Q5119890 unii "U8QXS1WU8G".
- Q5119890 type ChemicalSubstance.
- Q5119890 type Drug.
- Q5119890 type ChemicalObject.
- Q5119890 type Thing.
- Q5119890 type Q8386.
- Q5119890 comment "Ciglitazone (INN) is a thiazolidinedione. Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class.Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones.".
- Q5119890 label "Ciglitazone".
- Q5119890 depiction Ciglitazone.svg.