Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q5082273> ?p ?o }
Showing triples 1 to 84 of
84
with 100 triples per page.
- Q5082273 description "Clinical nutritionist".
- Q5082273 description "Clinical nutritionist".
- Q5082273 subject Q6047341.
- Q5082273 subject Q6508841.
- Q5082273 subject Q6563334.
- Q5082273 subject Q7064340.
- Q5082273 subject Q7214823.
- Q5082273 subject Q8341416.
- Q5082273 subject Q8505927.
- Q5082273 subject Q8751144.
- Q5082273 abstract "Template:ForCharles Saul Lieber (February 13, 1931 – March 1, 2009) was a clinical nutritionist who established that excess alcohol consumption can cause cirrhosis of the liver even in subjects who have an adequate diet, contradicting then-current scientific opinion.Lieber was born on February 13, 1931, in Antwerp, Belgium, and was forced to flee with his family to France, and later Switzerland, as World War II bloomed. He spent most of the war with a Swiss family that had taken him in from a refugee camp. He attended college in Belgium after the war, where a portion of his stomach was removed due to complications of a peptic ulcer. At the University of Brussels school of medicine, his ulcer led him to investigate its causes, prior to his graduation in 1955.He continued research there after graduation, until a fellowship took him to Boston City Hospital and Harvard University. There he was troubled by the belief in the profession that cirrhosis in alcoholics was caused by malnutrition and not alcohol itself, having seen alcoholics in Belgium who had liver disease even with a proper diet and based on research by Dr. Charles Best (co-discoverer of insulin) that showed that alcohol had no greater an effect in rats than sugar water. Lieber pursued Best's theory that excessive amounts of alcohol damaged the liver.He was hired by Manhattan's Bellevue Hospital Center in 1963, where he successfully pleaded for a grant from the National Institutes of Health which would be used for his investigations on alcohol in baboons. He was admitted to the faculty of Bronx Veterans Affairs Medical Center and was appointed as a professor at the Mount Sinai School of Medicine in 1968, where he identified the biochemical processes used in the human body to metabolize alcohol. In a 1974 study, he showed that baboons who had been given a normal diet combined with the equivalent of about 750 millilitres (26 imp fl oz; 25 US fl oz) of alcohol daily for four years experienced cirrhosis, contradicting medical dogma that inadequate nutrition combined with alcoholism caused the disease. Other research showed that the effect of even social drinking on the liver can cause it to create toxic substances, increasing the sensitivity of even social drinkers to acetaminophen, anesthetics and certain solventsLieber found that administering antibiotics to alcoholics with liver disease caused by their condition would have less ammonia converted from urea in their stomach, which he credited to bacteria in the stomach that he had seen using his microscope and that had been killed by the antibiotic treatment. As the medical wisdom at the time stated that bacteria could not survive in the stomach's acidic environment, his research was largely ignored. It was not until the 1980s, when researchers Dr. Barry Marshall and Dr. Robin Warren identified the bacteria Helicobacter pylori in the stomach as a cause of ulcers and stomach cancer, for which they won the 2005 Nobel Prize in Physiology or Medicine.He pushed the National Council on Alcoholism and Drug Dependence to create the journal Alcoholism: Clinical and Experimental Research in 1977 as an academic journal for articles regarding alcohol abuse and its treatment, to disseminate research in a field that was minimized by other medical professionals who did not believe that alcohol research was a legitimate avenue for research and that there was nothing medicine could do to address the problems of alcoholism.A 1990 study published in the New England Journal of Medicine showed that women feel greater effects than men from equivalent amounts of alcohol adjusted for body size due to lower amounts of a stomach enzyme that metabolizes the alcohol and keeps it from entering the bloodstream, though the study did not explain the cause of this enzymatic discrepancy. Lieber indicated that this finding might account for why women who become alcoholics are more likely to experience liver damage.Other research performed by Lieber showed that hepatitis could be triggered by consumption of alcohol. He pioneered the therapeutic use of the coenzyme S-Adenosyl methionine as a therapeutic means to prevent liver toxicity.Lieber died at age 78 on March 1, 2009 of stomach cancer at his home in Tenafly, New Jersey. Lieber was survived by his second wife, Dr. Maria Leo-Lieber, as well as three daughters, two sons and six grandchildren. His earlier marriage, to Adele Tornhadjm, ended in divorce.".
- Q5082273 birthDate "1931-02-13".
- Q5082273 birthPlace Q12892.
- Q5082273 birthPlace Q31.
- Q5082273 birthYear "1931".
- Q5082273 deathDate "2009-03-01".
- Q5082273 deathPlace Q1013254.
- Q5082273 deathYear "2009".
- Q5082273 wikiPageWikiLink Q1013254.
- Q5082273 wikiPageWikiLink Q11299.
- Q5082273 wikiPageWikiLink Q12892.
- Q5082273 wikiPageWikiLink Q131742.
- Q5082273 wikiPageWikiLink Q13371.
- Q5082273 wikiPageWikiLink Q142.
- Q5082273 wikiPageWikiLink Q147778.
- Q5082273 wikiPageWikiLink Q15326.
- Q5082273 wikiPageWikiLink Q159429.
- Q5082273 wikiPageWikiLink Q172941.
- Q5082273 wikiPageWikiLink Q180556.
- Q5082273 wikiPageWikiLink Q189588.
- Q5082273 wikiPageWikiLink Q1950740.
- Q5082273 wikiPageWikiLink Q201312.
- Q5082273 wikiPageWikiLink Q202136.
- Q5082273 wikiPageWikiLink Q20754971.
- Q5082273 wikiPageWikiLink Q208670.
- Q5082273 wikiPageWikiLink Q21163221.
- Q5082273 wikiPageWikiLink Q2576499.
- Q5082273 wikiPageWikiLink Q2894927.
- Q5082273 wikiPageWikiLink Q31.
- Q5082273 wikiPageWikiLink Q362.
- Q5082273 wikiPageWikiLink Q39.
- Q5082273 wikiPageWikiLink Q390551.
- Q5082273 wikiPageWikiLink Q407280.
- Q5082273 wikiPageWikiLink Q4087.
- Q5082273 wikiPageWikiLink Q4713331.
- Q5082273 wikiPageWikiLink Q48318.
- Q5082273 wikiPageWikiLink Q4947980.
- Q5082273 wikiPageWikiLink Q4990531.
- Q5082273 wikiPageWikiLink Q57055.
- Q5082273 wikiPageWikiLink Q582728.
- Q5082273 wikiPageWikiLink Q6047341.
- Q5082273 wikiPageWikiLink Q6508841.
- Q5082273 wikiPageWikiLink Q6563334.
- Q5082273 wikiPageWikiLink Q6971957.
- Q5082273 wikiPageWikiLink Q7064340.
- Q5082273 wikiPageWikiLink Q7214823.
- Q5082273 wikiPageWikiLink Q80061.
- Q5082273 wikiPageWikiLink Q8341416.
- Q5082273 wikiPageWikiLink Q8505927.
- Q5082273 wikiPageWikiLink Q867690.
- Q5082273 wikiPageWikiLink Q8751144.
- Q5082273 wikiPageWikiLink Q9368.
- Q5082273 dateOfBirth "1931-02-13".
- Q5082273 dateOfDeath "2009-03-01".
- Q5082273 name "Lieber, Charles S.".
- Q5082273 placeOfBirth Q12892.
- Q5082273 placeOfBirth Q31.
- Q5082273 placeOfDeath Q1013254.
- Q5082273 shortDescription "Clinical nutritionist".
- Q5082273 type Person.
- Q5082273 type Agent.
- Q5082273 type Person.
- Q5082273 type Agent.
- Q5082273 type NaturalPerson.
- Q5082273 type Thing.
- Q5082273 type Q215627.
- Q5082273 type Q5.
- Q5082273 type Person.
- Q5082273 comment "Template:ForCharles Saul Lieber (February 13, 1931 – March 1, 2009) was a clinical nutritionist who established that excess alcohol consumption can cause cirrhosis of the liver even in subjects who have an adequate diet, contradicting then-current scientific opinion.Lieber was born on February 13, 1931, in Antwerp, Belgium, and was forced to flee with his family to France, and later Switzerland, as World War II bloomed.".
- Q5082273 label "Charles S. Lieber".
- Q5082273 givenName "Charles S.".
- Q5082273 name "Charles S. Lieber".
- Q5082273 name "Lieber, Charles S.".
- Q5082273 surname "Lieber".