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- Q5008166 subject Q6980517.
- Q5008166 abstract "C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue anaphylatoxin that binds to the C3a receptor (C3aR), a class A G protein-coupled receptor. It plays a large role in the immune response.C3a molecules induce responses through the GPCR C3a receptor. Like other anaphylatoxins, C3a is regulated by cleavage of its carboxy-terminal arginine, resulting in C3a desarginine, which possesses lowered biological functions[8].C3a is an anaphylatoxin effector of the complement system with a range of functions including T cell activation and survival, chemotaxis, angiogenesis stimulation, mast cell degranulation, and macrophage activation. It has been shown to have both proinflammatory and anti-inflammatory responses, its activity able to counteract the proinflammatory effects of C5a. It has also been shown to regulate monocyte production of IL-1β.".
- Q5008166 thumbnail Complement_pathway.svg?width=300.
- Q5008166 wikiPageExternalLink ch163d.html.
- Q5008166 wikiPageWikiLink Q14874317.
- Q5008166 wikiPageWikiLink Q16460162.
- Q5008166 wikiPageWikiLink Q1999093.
- Q5008166 wikiPageWikiLink Q212354.
- Q5008166 wikiPageWikiLink Q2638593.
- Q5008166 wikiPageWikiLink Q38173.
- Q5008166 wikiPageWikiLink Q4118278.
- Q5008166 wikiPageWikiLink Q424292.
- Q5008166 wikiPageWikiLink Q4678002.
- Q5008166 wikiPageWikiLink Q5008114.
- Q5008166 wikiPageWikiLink Q5008164.
- Q5008166 wikiPageWikiLink Q5038090.
- Q5008166 wikiPageWikiLink Q658145.
- Q5008166 wikiPageWikiLink Q6980517.
- Q5008166 comment "C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue anaphylatoxin that binds to the C3a receptor (C3aR), a class A G protein-coupled receptor. It plays a large role in the immune response.C3a molecules induce responses through the GPCR C3a receptor.".
- Q5008166 label "C3a (complement)".
- Q5008166 depiction Complement_pathway.svg.
