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- Q475086 subject Q8374843.
- Q475086 abstract "Aggressive fibromatosis is a rare condition marked by the presence of desmoid tumors. Desmoid tumors are tumors that arise from cells called fibroblasts. Fibroblasts are found throughout our body and their main function is to provide structural support and protection to the vital organs such as lung, liver, blood vessels, heart, kidneys, skin, intestines etc. and they also play a critical role in wound healing. When fibroblast cells undergo mutations they can become cancerous and become desmoid tumors (also known as "aggressive fibromatosis"). Desmoid tumors can arise in virtually any part of the body. These tumors often occur in women in their 30's, but can occur in anyone at any age. Desmoid tumors can be slow growing or extremely aggressive. These are slow-growing musculoaponeurotic tumors without any metastatic potential. However, aggressive fibromatosis is locally aggressive. When they are aggressive they can cause life threatening problems or even death when they compress vital organs such as intestines, kidney, lungs, blood vessels, nerves etc. Most cases are sporadic, but some are associated with familial adenomatous polyposis (FAP). Approximately 10% of individuals with Gardner's syndrome, a type of FAP with extracolonic features, have desmoid tumors.Histologically they resemble very low-grade fibrosarcomas, but they are very locally aggressive and tend to recur even after complete resection. There is a tendency for recurrence in the setting of prior surgery; in one study, two-thirds of patients with desmoid tumors had a history of prior abdominal surgery.Risk factors for desmoid disease amongst FAP patients include female sex, a 3' APC mutation, a positive family history and a history of previous abdominal surgery.".
- Q475086 icd10 "D48.1".
- Q475086 meshId "D018222".
- Q475086 thumbnail MRI_desmoid_T1_fl2d_FS.jpg?width=300.
- Q475086 wikiPageExternalLink fibromatosis.html.
- Q475086 wikiPageExternalLink www.dtrf.org.
- Q475086 wikiPageExternalLink www.polyposisregistry.org.uk.
- Q475086 wikiPageWikiLink Q1064904.
- Q475086 wikiPageWikiLink Q1362453.
- Q475086 wikiPageWikiLink Q1369011.
- Q475086 wikiPageWikiLink Q14883378.
- Q475086 wikiPageWikiLink Q1541222.
- Q475086 wikiPageWikiLink Q1702335.
- Q475086 wikiPageWikiLink Q177094.
- Q475086 wikiPageWikiLink Q180507.
- Q475086 wikiPageWikiLink Q181876.
- Q475086 wikiPageWikiLink Q188724.
- Q475086 wikiPageWikiLink Q246809.
- Q475086 wikiPageWikiLink Q277954.
- Q475086 wikiPageWikiLink Q354111.
- Q475086 wikiPageWikiLink Q40821.
- Q475086 wikiPageWikiLink Q412178.
- Q475086 wikiPageWikiLink Q421136.
- Q475086 wikiPageWikiLink Q4774709.
- Q475086 wikiPageWikiLink Q8374843.
- Q475086 wikiPageWikiLink Q9597.
- Q475086 wikiPageWikiLink Q974135.
- Q475086 icd "D48.1".
- Q475086 meshid "D018222".
- Q475086 name "Aggressive fibromatosis".
- Q475086 type Disease.
- Q475086 type Thing.
- Q475086 type Q12136.
- Q475086 comment "Aggressive fibromatosis is a rare condition marked by the presence of desmoid tumors. Desmoid tumors are tumors that arise from cells called fibroblasts. Fibroblasts are found throughout our body and their main function is to provide structural support and protection to the vital organs such as lung, liver, blood vessels, heart, kidneys, skin, intestines etc. and they also play a critical role in wound healing.".
- Q475086 label "Aggressive fibromatosis".
- Q475086 depiction MRI_desmoid_T1_fl2d_FS.jpg.
- Q475086 name "Aggressive fibromatosis".