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- Q4746184 subject Q15211845.
- Q4746184 subject Q52361.
- Q4746184 subject Q6865951.
- Q4746184 subject Q7469560.
- Q4746184 abstract "Amiflamine (FLA-336) is a reversible inhibitor of monoamine oxidase A (MAO-A), thereby being a RIMA, and, to a lesser extent, semicarbazide-sensitive amine oxidase (SSAO), as well as a serotonin releasing agent (SRA). It is a derivative of the phenethylamine and amphetamine chemical classes. The (+)-enantiomer is the active stereoisomer.Amiflamine is unique among MAOIs in that it shows preference for inhibiting MAO-A in serotonergic relative to noradrenergic and dopaminergic neurons. In other words, at low doses, it can be used to selectively inhibit MAO-A enzymes in serotonin cells, whereas at higher doses it loses its selectivity. This property is attributed to amiflamine's higher affinity for the serotonin transporter over the norepinephrine and dopamine transporters, as transporter-mediated carriage is required for amiflamine to enter monoaminergic neurons.".
- Q4746184 atcPrefix "none".
- Q4746184 casNumber "77518-07-1".
- Q4746184 fdaUniiCode "NE25WV9C8S".
- Q4746184 iupacName "4-[(2S)-2-aminopropyl]-N,N,3-trimethylaniline".
- Q4746184 pubchem "71221".
- Q4746184 thumbnail Amiflamine.svg?width=300.
- Q4746184 wikiPageWikiLink Q14860818.
- Q4746184 wikiPageWikiLink Q14865372.
- Q4746184 wikiPageWikiLink Q14874257.
- Q4746184 wikiPageWikiLink Q14888415.
- Q4746184 wikiPageWikiLink Q15211845.
- Q4746184 wikiPageWikiLink Q186242.
- Q4746184 wikiPageWikiLink Q235816.
- Q4746184 wikiPageWikiLink Q2445303.
- Q4746184 wikiPageWikiLink Q3313599.
- Q4746184 wikiPageWikiLink Q410954.
- Q4746184 wikiPageWikiLink Q422693.
- Q4746184 wikiPageWikiLink Q427492.
- Q4746184 wikiPageWikiLink Q43054.
- Q4746184 wikiPageWikiLink Q4590759.
- Q4746184 wikiPageWikiLink Q461076.
- Q4746184 wikiPageWikiLink Q494483.
- Q4746184 wikiPageWikiLink Q52361.
- Q4746184 wikiPageWikiLink Q6125539.
- Q4746184 wikiPageWikiLink Q6865951.
- Q4746184 wikiPageWikiLink Q732744.
- Q4746184 wikiPageWikiLink Q7455052.
- Q4746184 wikiPageWikiLink Q7469560.
- Q4746184 wikiPageWikiLink Q898317.
- Q4746184 wikiPageWikiLink Q899107.
- Q4746184 atcPrefix "none".
- Q4746184 casNumber "77518".
- Q4746184 iupacName "4".
- Q4746184 pubchem "71221".
- Q4746184 unii "NE25WV9C8S".
- Q4746184 type ChemicalSubstance.
- Q4746184 type Drug.
- Q4746184 type ChemicalObject.
- Q4746184 type Thing.
- Q4746184 type Q8386.
- Q4746184 comment "Amiflamine (FLA-336) is a reversible inhibitor of monoamine oxidase A (MAO-A), thereby being a RIMA, and, to a lesser extent, semicarbazide-sensitive amine oxidase (SSAO), as well as a serotonin releasing agent (SRA). It is a derivative of the phenethylamine and amphetamine chemical classes. The (+)-enantiomer is the active stereoisomer.Amiflamine is unique among MAOIs in that it shows preference for inhibiting MAO-A in serotonergic relative to noradrenergic and dopaminergic neurons.".
- Q4746184 label "Amiflamine".
- Q4746184 depiction Amiflamine.svg.