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- Q4688294 subject Q9089708.
- Q4688294 abstract "In molecular biology, aerolysin is a cytolytic pore-forming toxin exported by Aeromonas hydrophila, a Gram-negative bacterium associated with diarrhoeal diseases and deep wound infections. The mature toxin binds to eukaryotic cells and aggregates to form holes (approximately 3 nm in diameter) leading to the destruction of the membrane permeability barrier and osmotic lysis. The structure of proaerolysin has been determined to 2.8A resolution and shows the protoxin to adopt a novel fold. Images of an aerolysin oligomer derived from electron microscopy and molecular dynamics simulations have helped to construct a model of the protein in its heptameric conformation, and to outline a mechanism by which this assembly might insert into lipid bilayers to form ion channels.".
- Q4688294 symbol "Aerolysin".
- Q4688294 thumbnail PDB_1pre_EBI.jpg?width=300.
- Q4688294 wikiPageWikiLink Q10876.
- Q4688294 wikiPageWikiLink Q12136.
- Q4688294 wikiPageWikiLink Q1218293.
- Q4688294 wikiPageWikiLink Q132560.
- Q4688294 wikiPageWikiLink Q15712714.
- Q4688294 wikiPageWikiLink Q166231.
- Q4688294 wikiPageWikiLink Q167149.
- Q4688294 wikiPageWikiLink Q178674.
- Q4688294 wikiPageWikiLink Q184753.
- Q4688294 wikiPageWikiLink Q19088.
- Q4688294 wikiPageWikiLink Q2697755.
- Q4688294 wikiPageWikiLink Q29548.
- Q4688294 wikiPageWikiLink Q423279.
- Q4688294 wikiPageWikiLink Q62536.
- Q4688294 wikiPageWikiLink Q632006.
- Q4688294 wikiPageWikiLink Q7230047.
- Q4688294 wikiPageWikiLink Q726004.
- Q4688294 wikiPageWikiLink Q7868.
- Q4688294 wikiPageWikiLink Q8054.
- Q4688294 wikiPageWikiLink Q847556.
- Q4688294 wikiPageWikiLink Q901663.
- Q4688294 wikiPageWikiLink Q9089708.
- Q4688294 symbol "Aerolysin".
- Q4688294 type Biomolecule.
- Q4688294 type Protein.
- Q4688294 type Thing.
- Q4688294 type Q206229.
- Q4688294 type Q8054.
- Q4688294 comment "In molecular biology, aerolysin is a cytolytic pore-forming toxin exported by Aeromonas hydrophila, a Gram-negative bacterium associated with diarrhoeal diseases and deep wound infections. The mature toxin binds to eukaryotic cells and aggregates to form holes (approximately 3 nm in diameter) leading to the destruction of the membrane permeability barrier and osmotic lysis. The structure of proaerolysin has been determined to 2.8A resolution and shows the protoxin to adopt a novel fold.".
- Q4688294 label "Aerolysin".
- Q4688294 depiction PDB_1pre_EBI.jpg.