Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q4596899> ?p ?o }
Showing triples 1 to 33 of
33
with 100 triples per page.
- Q4596899 subject Q8235519.
- Q4596899 subject Q8390786.
- Q4596899 subject Q8530593.
- Q4596899 subject Q8679151.
- Q4596899 abstract "(–)-2-Methoxyethyl-18-methoxycoronaridinate (ME-18-MC) is a second generation synthetic derivative of ibogaine developed by the research team led by the pharmacologist Stanley D. Glick from the Albany Medical College and the chemist Martin E. Kuehne from the University of Vermont. In animal studies it has shown similar efficacy to the related compound 18-methoxycoronaridine (18-MC) at reducing self-administration of morphine and methamphetamine but with higher potency by weight, showing anti-addictive effects at the equivalent of half the minimum effective dose of 18-MC. Similarly to 18-MC itself, ME-18-MC acts primarily as a selective α3β4 nicotinic acetylcholine antagonist, although it has a slightly stronger effect than 18-MC as an NMDA antagonist, and its effects on opioid receptors are weaker than those of 18-MC at all except the kappa opioid receptor, at which it has slightly higher affinity than 18-MC.".
- Q4596899 pubchem "10070278".
- Q4596899 thumbnail ME-18-MC_structure.png?width=300.
- Q4596899 wikiPageWikiLink Q1048898.
- Q4596899 wikiPageWikiLink Q14897645.
- Q4596899 wikiPageWikiLink Q191924.
- Q4596899 wikiPageWikiLink Q200107.
- Q4596899 wikiPageWikiLink Q4044974.
- Q4596899 wikiPageWikiLink Q409455.
- Q4596899 wikiPageWikiLink Q421797.
- Q4596899 wikiPageWikiLink Q4553714.
- Q4596899 wikiPageWikiLink Q4709349.
- Q4596899 wikiPageWikiLink Q5015902.
- Q4596899 wikiPageWikiLink Q5172181.
- Q4596899 wikiPageWikiLink Q7051224.
- Q4596899 wikiPageWikiLink Q81225.
- Q4596899 wikiPageWikiLink Q8235519.
- Q4596899 wikiPageWikiLink Q8390786.
- Q4596899 wikiPageWikiLink Q8530593.
- Q4596899 wikiPageWikiLink Q8679151.
- Q4596899 pubchem "10070278".
- Q4596899 type ChemicalSubstance.
- Q4596899 type Drug.
- Q4596899 type ChemicalObject.
- Q4596899 type Thing.
- Q4596899 type Q8386.
- Q4596899 comment "(–)-2-Methoxyethyl-18-methoxycoronaridinate (ME-18-MC) is a second generation synthetic derivative of ibogaine developed by the research team led by the pharmacologist Stanley D. Glick from the Albany Medical College and the chemist Martin E. Kuehne from the University of Vermont.".
- Q4596899 label "2-Methoxyethyl-18-methoxycoronaridinate".
- Q4596899 depiction ME-18-MC_structure.png.