Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q425941> ?p ?o }
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- Q425941 subject Q7204727.
- Q425941 subject Q8810351.
- Q425941 abstract "Protein A is a 42 kDa surface protein originally found in the cell wall of the bacterium Staphylococcus aureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two-component system called ArlS-ArlR. It has found use in biochemical research because of its ability to bind immunoglobulins. It is composed of five homologous Ig-binding domains that fold into a three-helix bundle. Each domain is able to bind proteins from many mammalian species, most notably IgGs. It binds the heavy chain within the Fc region of most immunoglobulins and also within the Fab region in the case of the human VH3 family. Through these interactions in serum, where IgG molecules are bound in the wrong orientation (in relation to normal antibody function), the bacteria disrupts opsonization and phagocytosis.".
- Q425941 symbol "SpA".
- Q425941 thumbnail Protein_A_1DEE_1L6X.png?width=300.
- Q425941 wikiPageWikiLink Q10876.
- Q425941 wikiPageWikiLink Q110084.
- Q425941 wikiPageWikiLink Q1616930.
- Q425941 wikiPageWikiLink Q181354.
- Q425941 wikiPageWikiLink Q184726.
- Q425941 wikiPageWikiLink Q188121.
- Q425941 wikiPageWikiLink Q193889.
- Q425941 wikiPageWikiLink Q232956.
- Q425941 wikiPageWikiLink Q2448456.
- Q425941 wikiPageWikiLink Q390697.
- Q425941 wikiPageWikiLink Q420107.
- Q425941 wikiPageWikiLink Q424403.
- Q425941 wikiPageWikiLink Q483261.
- Q425941 wikiPageWikiLink Q7204727.
- Q425941 wikiPageWikiLink Q7251427.
- Q425941 wikiPageWikiLink Q7251440.
- Q425941 wikiPageWikiLink Q79448.
- Q425941 wikiPageWikiLink Q79460.
- Q425941 wikiPageWikiLink Q8047.
- Q425941 wikiPageWikiLink Q8054.
- Q425941 wikiPageWikiLink Q8810351.
- Q425941 wikiPageWikiLink Q900961.
- Q425941 wikiPageWikiLink Q901305.
- Q425941 wikiPageWikiLink Q909628.
- Q425941 symbol "SpA".
- Q425941 type Biomolecule.
- Q425941 type Protein.
- Q425941 type Thing.
- Q425941 type Q206229.
- Q425941 type Q8054.
- Q425941 comment "Protein A is a 42 kDa surface protein originally found in the cell wall of the bacterium Staphylococcus aureus. It is encoded by the spa gene and its regulation is controlled by DNA topology, cellular osmolarity, and a two-component system called ArlS-ArlR. It has found use in biochemical research because of its ability to bind immunoglobulins. It is composed of five homologous Ig-binding domains that fold into a three-helix bundle.".
- Q425941 label "Protein A".
- Q425941 depiction Protein_A_1DEE_1L6X.png.