Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q422618> ?p ?o }
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- Q422618 abstract "Ritonavir, sold under the trade name Norvir, is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy (HAART). Often a low dose is used with other protease inhibitors. It may also be used in combination with other medications for hepatitis C. It is taken by mouth.Common side effects include nausea, vomiting, loss of appetite, diarrhea, and numbness of the hands and feet. Serious side effects include liver problems, pancreatitis, allergic reactions, and arrythmias. Serious interactions may occur with a number of other medications including amiodarone and simvastatin. At low doses it is considered to be okay during pregnancy. Ritonavir is of the protease inhibitor class. It is often used to inhibit the enzyme that metabolizes other protease inhibitors. This inhibition leads to higher concentrations of these latter medication.Ritonavir first came into use in 1996. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. The capsules of the medication do not work the same as the tablets. Globally the wholesale cost is between 0.07 and 2.20 USD per day. In the United States it costs about 9.20 to 55 USD per day depending on the dose.".
- Q422618 atcPrefix "J05".
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- Q422618 casNumber "155213-67-5".
- Q422618 chEBI "45409".
- Q422618 drugbank "DB00503".
- Q422618 fdaUniiCode "O3J8G9O825".
- Q422618 iupacName "1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}butanamido]-1,6-diphenylhexan-2-yl]carbamate".
- Q422618 pubchem "392622".
- Q422618 thumbnail Ritonavir_structure.svg?width=300.
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- Q422618 atcPrefix "J05".
- Q422618 atcSuffix "AE03".
- Q422618 casNumber "155213".
- Q422618 chebi "45409".
- Q422618 drugbank "DB00503".
- Q422618 iupacName "13".
- Q422618 pubchem "392622".
- Q422618 unii "O3J8G9O825".
- Q422618 type ChemicalSubstance.
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- Q422618 comment "Ritonavir, sold under the trade name Norvir, is an antiretroviral medication used along with other medications to treat HIV/AIDS This combination treatment is known as highly active antiretroviral therapy (HAART). Often a low dose is used with other protease inhibitors. It may also be used in combination with other medications for hepatitis C. It is taken by mouth.Common side effects include nausea, vomiting, loss of appetite, diarrhea, and numbness of the hands and feet.".
- Q422618 label "Ritonavir".