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- Q421344 subject Q9444764.
- Q421344 abstract "Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.Examples include: Haloperidol, the most widely used classical antipsychotic drug in this class Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine) Trifluperidol, a highly potent antipsychotic (100 times more potent than chlorpromazine) Melperone, a weakly potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients Lenperone Azaperone, used in veterinary medicine Domperidone, a dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself). Fluanisone Penfluridol Pipamperone Spiperone (more potent neuroleptic than benperidol) NonaperoneCloroperoneThe atypical antipsychotic risperidone, although not a butyrophenone, was developed with the structures of benperidol and ketanserin as a basis.Ketocaine is a butyrophenone local anesthetic.Fluspiperone is the butyrophenone equivalent of the diphenylbutylpiperidine based antipsychotic FluspirileneIn the case of Spirilene, the butyrophenone is methylated with one equivalent of Grignard reagent and the corresponding tertiary alcohol is then dehydrated to an olefin.Halopemide is similar to a butyrophenone antipsychotic in which the methylene carbon closest to the carbonyl is replaced with a secondary nitrogen so that the structure become benzamide based.↑ 1.0 1.1 1.2 ↑ ↑ ↑".
- Q421344 iupacName "1-phenylbutan-1-one".
- Q421344 thumbnail Butyrophenone.svg?width=300.
- Q421344 wikiPageWikiLink Q160796.
- Q421344 wikiPageWikiLink Q170201.
- Q421344 wikiPageWikiLink Q174259.
- Q421344 wikiPageWikiLink Q1868462.
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- Q421344 wikiPageWikiLink Q208144.
- Q421344 wikiPageWikiLink Q2149707.
- Q421344 wikiPageWikiLink Q251347.
- Q421344 wikiPageWikiLink Q3077150.
- Q421344 wikiPageWikiLink Q394129.
- Q421344 wikiPageWikiLink Q407972.
- Q421344 wikiPageWikiLink Q408300.
- Q421344 wikiPageWikiLink Q41112.
- Q421344 wikiPageWikiLink Q412443.
- Q421344 wikiPageWikiLink Q415118.
- Q421344 wikiPageWikiLink Q415972.
- Q421344 wikiPageWikiLink Q415997.
- Q421344 wikiPageWikiLink Q417731.
- Q421344 wikiPageWikiLink Q424238.
- Q421344 wikiPageWikiLink Q424412.
- Q421344 wikiPageWikiLink Q4463264.
- Q421344 wikiPageWikiLink Q4832244.
- Q421344 wikiPageWikiLink Q5279740.
- Q421344 wikiPageWikiLink Q5462605.
- Q421344 wikiPageWikiLink Q557945.
- Q421344 wikiPageWikiLink Q575136.
- Q421344 wikiPageWikiLink Q6523202.
- Q421344 wikiPageWikiLink Q758295.
- Q421344 wikiPageWikiLink Q9444764.
- Q421344 iupacname "1".
- Q421344 type ChemicalCompound.
- Q421344 type ChemicalSubstance.
- Q421344 type ChemicalObject.
- Q421344 type Thing.
- Q421344 type Q11173.
- Q421344 comment "Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.Examples include: Haloperidol, the most widely used classical antipsychotic drug in this class Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine) Trifluperidol, a highly potent antipsychotic (100 times more potent than chlorpromazine) Melperone, a weakly potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients Lenperone Azaperone, used in veterinary medicine Domperidone, a dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself). ".
- Q421344 label "Butyrophenone".
- Q421344 depiction Butyrophenone.svg.