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- Q421091 subject Q6442932.
- Q421091 subject Q7029794.
- Q421091 subject Q7215865.
- Q421091 subject Q7334142.
- Q421091 subject Q8264664.
- Q421091 subject Q8412954.
- Q421091 subject Q8503308.
- Q421091 subject Q8919936.
- Q421091 abstract "Levocetirizine (as levocetirizine dihydrochloride) is a third-generation non-sedative antihistamine, developed from the second-generation antihistamine cetirizine. Chemically, levocetirizine is the active enantiomer of cetirizine. It is the R-enantiomer of the cetirizine racemate. Levocetirizine is an inverse agonist that decreases activity at histamine H1 receptors. This in turn prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of hay fever. It does not prevent the actual release of histamine from mast cells.The manufacturers claim it to be more effective with fewer side effects than the second-generation drugs; however, there have been no published studies supporting this assertion. A study part-funded by the manufacturer UCB concluded it may be more effective than some other second- and third-generation anti-histamines, but didn't compare it to cetirizine.".
- Q421091 atcPrefix "R06".
- Q421091 atcSuffix "AE09".
- Q421091 casNumber "130018-77-8".
- Q421091 fdaUniiCode "6U5EA9RT2O".
- Q421091 iupacName "2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid".
- Q421091 pubchem "1549000".
- Q421091 thumbnail Levocetirizine_structure_2.svg?width=300.
- Q421091 wikiPageExternalLink Xyzal_PI_%2012_2010.pdf.
- Q421091 wikiPageWikiLink Q1077823.
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- Q421091 wikiPageWikiLink Q494483.
- Q421091 wikiPageWikiLink Q6442932.
- Q421091 wikiPageWikiLink Q7029794.
- Q421091 wikiPageWikiLink Q7215865.
- Q421091 wikiPageWikiLink Q7334142.
- Q421091 wikiPageWikiLink Q7431046.
- Q421091 wikiPageWikiLink Q818092.
- Q421091 wikiPageWikiLink Q8264664.
- Q421091 wikiPageWikiLink Q837.
- Q421091 wikiPageWikiLink Q8412954.
- Q421091 wikiPageWikiLink Q8503308.
- Q421091 wikiPageWikiLink Q86.
- Q421091 wikiPageWikiLink Q8919936.
- Q421091 wikiPageWikiLink Q902046.
- Q421091 wikiPageWikiLink Q9368.
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- Q421091 atcPrefix "R06".
- Q421091 atcSuffix "AE09".
- Q421091 casNumber "130018".
- Q421091 iupacName "2".
- Q421091 pubchem "1549000".
- Q421091 unii "6".
- Q421091 type ChemicalSubstance.
- Q421091 type Drug.
- Q421091 type ChemicalObject.
- Q421091 type Thing.
- Q421091 type Q8386.
- Q421091 comment "Levocetirizine (as levocetirizine dihydrochloride) is a third-generation non-sedative antihistamine, developed from the second-generation antihistamine cetirizine. Chemically, levocetirizine is the active enantiomer of cetirizine. It is the R-enantiomer of the cetirizine racemate. Levocetirizine is an inverse agonist that decreases activity at histamine H1 receptors.".
- Q421091 label "Levocetirizine".
- Q421091 depiction Levocetirizine_structure_2.svg.