Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q420377> ?p ?o }
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- Q420377 subject Q7145142.
- Q420377 subject Q7170959.
- Q420377 subject Q8600287.
- Q420377 subject Q8758634.
- Q420377 subject Q8965786.
- Q420377 abstract "Mexiletine (INN) (sold under the trade name Mexitil) is a non-selective voltage-gated sodium channel blocker which belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat arrhythmias within the heart, or seriously irregular heartbeats. It slows conduction in the heart and makes the heart tissue less sensitive. Dizziness, heartburn, nausea, nervousness, trembling, unsteadiness are common side effects. It is available in injection and capsule form.Class IB antiarrhythmics decrease action potential frequency by lengthening the repolarization phase. This is achieved by blocking sodium channels.This drug is now no longer freely available as a licensed product in either the US or the UK. It can be imported to the UK as an unlicensed, 'named-patient' drug. Its use in arrhythmias is restricted to use in life-threatening conditions only.Mexiletine may also be of use in patients experiencing refractory pain and is also effective for treating muscle stiffness resulting from myotonic dystrophy (Steinert's disease) or nondystrophic myotonias such as myotonia congenita (Thomsen disease).".
- Q420377 atcPrefix "C01".
- Q420377 atcSuffix "BB02".
- Q420377 bioavailability "90.0".
- Q420377 casNumber "31828-71-4".
- Q420377 chEBI "6916".
- Q420377 drugbank "DB00379".
- Q420377 fdaUniiCode "1U511HHV4Z".
- Q420377 iupacName "(RS)-1-(2,6-dimethylphenoxy)propan-2-amine".
- Q420377 iupacName "2-(2-aminopropoxy)-1,3-dimethylbenzene".
- Q420377 iupacName "OR".
- Q420377 pubchem "4178".
- Q420377 thumbnail Mexiletine.svg?width=300.
- Q420377 wikiPageExternalLink a607064.html.
- Q420377 wikiPageWikiLink Q1072.
- Q420377 wikiPageWikiLink Q14864427.
- Q420377 wikiPageWikiLink Q14890102.
- Q420377 wikiPageWikiLink Q1860507.
- Q420377 wikiPageWikiLink Q189331.
- Q420377 wikiPageWikiLink Q241549.
- Q420377 wikiPageWikiLink Q424960.
- Q420377 wikiPageWikiLink Q467717.
- Q420377 wikiPageWikiLink Q587420.
- Q420377 wikiPageWikiLink Q640448.
- Q420377 wikiPageWikiLink Q7145142.
- Q420377 wikiPageWikiLink Q7170959.
- Q420377 wikiPageWikiLink Q7553303.
- Q420377 wikiPageWikiLink Q81938.
- Q420377 wikiPageWikiLink Q824258.
- Q420377 wikiPageWikiLink Q8600287.
- Q420377 wikiPageWikiLink Q8758634.
- Q420377 wikiPageWikiLink Q8965786.
- Q420377 wikiPageWikiLink Q912887.
- Q420377 wikiPageWikiLink Q9368.
- Q420377 wikiPageWikiLink Q9377.
- Q420377 atcPrefix "1.0".
- Q420377 atcSuffix "BB02".
- Q420377 bioavailability "90.0".
- Q420377 casNumber "31828".
- Q420377 chebi "6916".
- Q420377 drugbank "DB00379".
- Q420377 iupacName "-1".
- Q420377 iupacName "2".
- Q420377 iupacName "OR".
- Q420377 pubchem "4178".
- Q420377 unii "1".
- Q420377 type ChemicalSubstance.
- Q420377 type Drug.
- Q420377 type ChemicalObject.
- Q420377 type Thing.
- Q420377 type Q8386.
- Q420377 comment "Mexiletine (INN) (sold under the trade name Mexitil) is a non-selective voltage-gated sodium channel blocker which belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat arrhythmias within the heart, or seriously irregular heartbeats. It slows conduction in the heart and makes the heart tissue less sensitive. Dizziness, heartburn, nausea, nervousness, trembling, unsteadiness are common side effects.".
- Q420377 label "Mexiletine".
- Q420377 depiction Mexiletine.svg.