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- Q419394 subject Q18924462.
- Q419394 subject Q20870732.
- Q419394 subject Q6442932.
- Q419394 subject Q7145146.
- Q419394 subject Q8210727.
- Q419394 subject Q8679151.
- Q419394 subject Q9052323.
- Q419394 abstract "Sevoflurane (1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane; synonym, fluoromethyl hexafluoroisopropyl ether), is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia. After desflurane, it is the volatile anesthetic with the fastest onset and offset.It is one of the most commonly used volatile anesthetic agents, particularly for outpatient anesthesia, and including in anesthesia of children and infants, and in veterinary medicine. Together with desflurane, sevoflurane is replacing isoflurane and halothane in modern anesthesiology. It is often administered in a mixture of nitrous oxide and oxygen.Sevoflurane "has an excellent safety record", but is under review for potential neurotoxicity, especially relevant to administration in infants and children, and rare reports similar to halothane hepatotoxicity. Sevoflurane is the preferred agent for mask induction due to its lesser irritation to mucous membranes.Sevoflurane was discovered by Ross Terrell and independently by Bernard M Regan. A detailed report of its development and properties appeared in 1975 in a paper authored by Richard Wallin, Bernard Regan, Martha Napoli and Ivan Stern it was introduced into clinical practice initially in Japan in 1990. The rights for sevoflurane in the US and other countries were held by Abbott Laboratories; it is available as a generic drug. Sevoflurane's name derives from the seven fluorine atoms in its substituents, alongside a standard suffix for such agents.".
- Q419394 atcPrefix "N01".
- Q419394 atcSuffix "AB08".
- Q419394 casNumber "28523-86-6".
- Q419394 chEBI "9130".
- Q419394 drugbank "DB01236".
- Q419394 fdaUniiCode "38LVP0K73A".
- Q419394 iupacName "1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane".
- Q419394 pubchem "5206".
- Q419394 thumbnail Sevoflurane.svg?width=300.
- Q419394 wikiPageExternalLink propofol_and_sevoflurane.htm.
- Q419394 wikiPageExternalLink Sevoflurane__A_Review_of_its_Pharmacodynamic_and.9.aspx.
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- Q419394 wikiPageWikiLink Q6442932.
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- Q419394 wikiPageWikiLink Q7145146.
- Q419394 wikiPageWikiLink Q8210727.
- Q419394 wikiPageWikiLink Q8679151.
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- Q419394 wikiPageWikiLink Q9052323.
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- Q419394 atcPrefix "N01".
- Q419394 atcSuffix "AB08".
- Q419394 casNumber "28523".
- Q419394 chebi "9130".
- Q419394 drugbank "DB01236".
- Q419394 iupacName "111333".
- Q419394 pubchem "5206".
- Q419394 unii "38".
- Q419394 type ChemicalSubstance.
- Q419394 type Drug.
- Q419394 type ChemicalObject.
- Q419394 type Thing.
- Q419394 type Q8386.
- Q419394 comment "Sevoflurane (1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane; synonym, fluoromethyl hexafluoroisopropyl ether), is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia.".
- Q419394 label "Sevoflurane".
- Q419394 depiction Sevoflurane.svg.