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- Q413248 subject Q7215429.
- Q413248 subject Q8374391.
- Q413248 abstract "A depsipeptide is a peptide in which one or more of its amide, -C(O)NHR-, groups are replaced by the corresponding ester, -C(O)OR, or more generally, is a molecule that has both peptide and ester linkages in proximity in the same amino acid-containing small molecule or chain. The ester moiety is generally an easily accomplished synthetic alteration, making depsipeptide tool compounds easy to prepare, e.g. in construction of alternative substrates for proteolytic enzymes. As well, nature has many pathways for production of this structural motif, and so depsipeptide natural products are relatively common, and are being studied in a variety of early preclinical therapeutic discovery contexts, including antiinfectives (toward discover of antibacterials and antivirals).".
- Q413248 thumbnail Depsipeptide_Principle_V.1.png?width=300.
- Q413248 wikiPageWikiLink Q101487.
- Q413248 wikiPageWikiLink Q1144013.
- Q413248 wikiPageWikiLink Q1153832.
- Q413248 wikiPageWikiLink Q12187.
- Q413248 wikiPageWikiLink Q130914.
- Q413248 wikiPageWikiLink Q1418791.
- Q413248 wikiPageWikiLink Q15410937.
- Q413248 wikiPageWikiLink Q15425795.
- Q413248 wikiPageWikiLink Q161249.
- Q413248 wikiPageWikiLink Q166231.
- Q413248 wikiPageWikiLink Q16850825.
- Q413248 wikiPageWikiLink Q16901191.
- Q413248 wikiPageWikiLink Q169324.
- Q413248 wikiPageWikiLink Q17153149.
- Q413248 wikiPageWikiLink Q172847.
- Q413248 wikiPageWikiLink Q178430.
- Q413248 wikiPageWikiLink Q188777.
- Q413248 wikiPageWikiLink Q218642.
- Q413248 wikiPageWikiLink Q3569101.
- Q413248 wikiPageWikiLink Q424027.
- Q413248 wikiPageWikiLink Q5012788.
- Q413248 wikiPageWikiLink Q595158.
- Q413248 wikiPageWikiLink Q7133208.
- Q413248 wikiPageWikiLink Q7215429.
- Q413248 wikiPageWikiLink Q7363205.
- Q413248 wikiPageWikiLink Q739867.
- Q413248 wikiPageWikiLink Q7578231.
- Q413248 wikiPageWikiLink Q8374391.
- Q413248 wikiPageWikiLink Q846227.
- Q413248 wikiPageWikiLink Q847556.
- Q413248 wikiPageWikiLink Q901227.
- Q413248 comment "A depsipeptide is a peptide in which one or more of its amide, -C(O)NHR-, groups are replaced by the corresponding ester, -C(O)OR, or more generally, is a molecule that has both peptide and ester linkages in proximity in the same amino acid-containing small molecule or chain. The ester moiety is generally an easily accomplished synthetic alteration, making depsipeptide tool compounds easy to prepare, e.g. in construction of alternative substrates for proteolytic enzymes.".
- Q413248 label "Depsipeptide".
- Q413248 depiction Depsipeptide_Principle_V.1.png.