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- Q411011 subject Q13285973.
- Q411011 subject Q8880051.
- Q411011 subject Q9532257.
- Q411011 abstract "Brevetoxin (PbTx), or brevetoxins, are a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis. Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes and causing the illness clinically described as neurotoxic shellfish poisoning (NSP).Although brevetoxins are most well-studied in K. brevis, they are also found in other species of Karenia and at least one large fish kill has been traced to brevetoxins in Chattonella.Other Brevetoxins:Brevetoxin-5 (PbTx-5): like PbTx-3, but acetylated hydroxyl group in position 38.Brevetoxin-6 (PbTx-6): like PbTx-2, but double bond 27-28 is epoxidated.Brevetoxin-B was synthesized in 1995 by K. C. Nicolaou and coworkers in 123 steps with 91% average yield (final yield ~9·10−6). and in 2004 a total of 90 steps with an average 93% yield for each step (0.14% overall).K. C. Nicolaou and coworkers reported their synthesis of Brevetoxin-1 in 1998. In 2009, Michael Crimmins and co-workers reported their synthesis of Brevetoxin-1 as well.".
- Q411011 thumbnail Brevetoxin_A.svg?width=300.
- Q411011 wikiPageWikiLink Q103230.
- Q411011 wikiPageWikiLink Q104116.
- Q411011 wikiPageWikiLink Q120490.
- Q411011 wikiPageWikiLink Q1211248.
- Q411011 wikiPageWikiLink Q13285973.
- Q411011 wikiPageWikiLink Q1420425.
- Q411011 wikiPageWikiLink Q16978219.
- Q411011 wikiPageWikiLink Q1775153.
- Q411011 wikiPageWikiLink Q293143.
- Q411011 wikiPageWikiLink Q326139.
- Q411011 wikiPageWikiLink Q355096.
- Q411011 wikiPageWikiLink Q408028.
- Q411011 wikiPageWikiLink Q424960.
- Q411011 wikiPageWikiLink Q426245.
- Q411011 wikiPageWikiLink Q5087960.
- Q411011 wikiPageWikiLink Q6370165.
- Q411011 wikiPageWikiLink Q796604.
- Q411011 wikiPageWikiLink Q8880051.
- Q411011 wikiPageWikiLink Q9532257.
- Q411011 comment "Brevetoxin (PbTx), or brevetoxins, are a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis. Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes and causing the illness clinically described as neurotoxic shellfish poisoning (NSP).Although brevetoxins are most well-studied in K.".
- Q411011 label "Brevetoxin".
- Q411011 depiction Brevetoxin_A.svg.