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- Q410789 subject Q6442932.
- Q410789 subject Q7335338.
- Q410789 subject Q8413416.
- Q410789 subject Q8492054.
- Q410789 subject Q9052781.
- Q410789 abstract "Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name pulmonext by MSN labs ) is a drug indicated for use in the treatment of pulmonary hypertension.The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA). Ambrisentan significantly improved exercise capacity (6-minute walk distance) compared with placebo in two double-blind, multicenter trials (ARIES-1 and ARIES-2).Ambrisentan was approved by the U.S. Food and Drug Administration (FDA) and European Medicines Agency, and designated an orphan drug, for the treatment of pulmonary hypertension.".
- Q410789 atcPrefix "C02".
- Q410789 atcSuffix "KX02".
- Q410789 casNumber "177036-94-1".
- Q410789 fdaUniiCode "HW6NV07QEC".
- Q410789 iupacName "(2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid".
- Q410789 pubchem "6918493".
- Q410789 thumbnail Ambrisentan_structure.svg?width=300.
- Q410789 wikiPageExternalLink www.letairis.com.
- Q410789 wikiPageExternalLink LETAIRIS_prescribing_information.pdf.
- Q410789 wikiPageExternalLink how_to_get_letairis.html.
- Q410789 wikiPageWikiLink Q1128595.
- Q410789 wikiPageWikiLink Q130146.
- Q410789 wikiPageWikiLink Q1367466.
- Q410789 wikiPageWikiLink Q204711.
- Q410789 wikiPageWikiLink Q390537.
- Q410789 wikiPageWikiLink Q390566.
- Q410789 wikiPageWikiLink Q390709.
- Q410789 wikiPageWikiLink Q424156.
- Q410789 wikiPageWikiLink Q5308827.
- Q410789 wikiPageWikiLink Q575278.
- Q410789 wikiPageWikiLink Q631521.
- Q410789 wikiPageWikiLink Q6442932.
- Q410789 wikiPageWikiLink Q7335338.
- Q410789 wikiPageWikiLink Q8413416.
- Q410789 wikiPageWikiLink Q8492054.
- Q410789 wikiPageWikiLink Q9052781.
- Q410789 atcPrefix "2.0".
- Q410789 atcSuffix "KX02".
- Q410789 casNumber "177036".
- Q410789 iupacName "-2".
- Q410789 pubchem "6918493".
- Q410789 unii "HW6NV07QEC".
- Q410789 type ChemicalSubstance.
- Q410789 type Drug.
- Q410789 type ChemicalObject.
- Q410789 type Thing.
- Q410789 type Q8386.
- Q410789 comment "Ambrisentan (U.S. trade name Letairis; E.U. trade name Volibris; India trade name pulmonext by MSN labs ) is a drug indicated for use in the treatment of pulmonary hypertension.The peptide endothelin constricts muscles in blood vessels, increasing blood pressure. Ambrisentan, which relaxes those muscles, is an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA).".
- Q410789 label "Ambrisentan".
- Q410789 depiction Ambrisentan_structure.svg.