Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q410663> ?p ?o }
Showing triples 1 to 46 of
46
with 100 triples per page.
- Q410663 subject Q5920511.
- Q410663 subject Q7579524.
- Q410663 subject Q8249906.
- Q410663 subject Q8252090.
- Q410663 subject Q9052323.
- Q410663 abstract "Fluoxymesterone (trade name Halotestin) is an anabolic steroid with strong androgenic properties that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women. It is approximately 5 times as potent as testosterone. The antitumor activity of fluoxymesterone appears related to reduction or competitive inhibition of prolactin receptors or estrogen receptors or production. Dissimilar to testosterone, halotestin has a 100% bioavailability, as the methylation of the 17α-position in halotestin inhibits hepatic metabolism by enzymatic oxidation of 17β-hydroxyl, allowing its absorption into the bloodstream for transport around the body. While there are many legitimate pharmaceutical applications of halotestin, it is also abused, leading to the development of analytical techniques by which halotestin doping can be identified.Like many C-17 alpha alkylated steroids, fluoxymesterone has poor binding to the androgen receptor. Even so, its actions are mediated by the androgen receptor, most-likely due to its prolonged plasma half-life which is approximately 9.2 hours.".
- Q410663 atcPrefix "G03".
- Q410663 atcSuffix "BA01".
- Q410663 bioavailability "100.0".
- Q410663 casNumber "76-43-7".
- Q410663 chEBI "5120".
- Q410663 drugbank "DB01185".
- Q410663 fdaUniiCode "9JU12S4YFY".
- Q410663 iupacName "9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one".
- Q410663 pubchem "6446".
- Q410663 thumbnail Fluoxymesterone_structure.svg?width=300.
- Q410663 wikiPageWikiLink Q101065.
- Q410663 wikiPageWikiLink Q1216998.
- Q410663 wikiPageWikiLink Q1318776.
- Q410663 wikiPageWikiLink Q14873015.
- Q410663 wikiPageWikiLink Q2575340.
- Q410663 wikiPageWikiLink Q309438.
- Q410663 wikiPageWikiLink Q5920511.
- Q410663 wikiPageWikiLink Q62614.
- Q410663 wikiPageWikiLink Q7579524.
- Q410663 wikiPageWikiLink Q8249906.
- Q410663 wikiPageWikiLink Q8252090.
- Q410663 wikiPageWikiLink Q9052323.
- Q410663 wikiPageWikiLink Q938107.
- Q410663 atcPrefix "G03".
- Q410663 atcSuffix "BA01".
- Q410663 bioavailability "100".
- Q410663 casNumber "76".
- Q410663 chebi "5120".
- Q410663 drugbank "DB01185".
- Q410663 iupacName "9".
- Q410663 pubchem "6446".
- Q410663 unii "9".
- Q410663 type ChemicalSubstance.
- Q410663 type Drug.
- Q410663 type ChemicalObject.
- Q410663 type Thing.
- Q410663 type Q8386.
- Q410663 comment "Fluoxymesterone (trade name Halotestin) is an anabolic steroid with strong androgenic properties that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women. It is approximately 5 times as potent as testosterone. The antitumor activity of fluoxymesterone appears related to reduction or competitive inhibition of prolactin receptors or estrogen receptors or production.".
- Q410663 label "Fluoxymesterone".
- Q410663 depiction Fluoxymesterone_structure.svg.