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- Q4035582 subject Q16812033.
- Q4035582 subject Q9016234.
- Q4035582 abstract "CD64 (Cluster of Differentiation 64) is a type of integral membrane glycoprotein known as an Fc receptor that binds monomeric IgG-type antibodies with high affinity. It is more commonly known as Fc-gamma receptor 1 (FcγRI). After binding IgG, CD64 interacts with an accessory chain known as the common γ chain (γ chain), which possesses an ITAM motif that is necessary for triggering cellular activation.Structurally CD64 is composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail.CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.There are three distinct (but highly similar) genes in humans for CD64 called FcγRIA (CD64A), FcγRIB (CD64B), and FcγRIC (CD64C) that are located on chromosome 1. These three genes produce six different mRNA transcripts ; two from CD64A, three from CD64B, and one from CD64C; by alternate splicing of the genes.".
- Q4035582 arm "p".
- Q4035582 arm "q".
- Q4035582 band "11.2".
- Q4035582 band "21.1".
- Q4035582 band "21.2".
- Q4035582 chromosome "1".
- Q4035582 entrezgene "2209".
- Q4035582 entrezgene "2210".
- Q4035582 entrezgene "2211".
- Q4035582 hgncid "3613".
- Q4035582 hgncid "3614".
- Q4035582 hgncid "3615".
- Q4035582 locusSupplementaryData "-21.3".
- Q4035582 omim "146760".
- Q4035582 omim "601502".
- Q4035582 omim "601503".
- Q4035582 refseq "NM_000566".
- Q4035582 refseq "NM_001004340".
- Q4035582 refseq "XM_001133198".
- Q4035582 symbol "FCGR1A".
- Q4035582 symbol "FCGR1B".
- Q4035582 symbol "FCGR1C".
- Q4035582 uniprot "P12314".
- Q4035582 uniprot "Q92637".
- Q4035582 wikiPageWikiLink Q1385443.
- Q4035582 wikiPageWikiLink Q1469784.
- Q4035582 wikiPageWikiLink Q14863119.
- Q4035582 wikiPageWikiLink Q16812033.
- Q4035582 wikiPageWikiLink Q1757382.
- Q4035582 wikiPageWikiLink Q178827.
- Q4035582 wikiPageWikiLink Q17927763.
- Q4035582 wikiPageWikiLink Q18027639.
- Q4035582 wikiPageWikiLink Q187126.
- Q4035582 wikiPageWikiLink Q188928.
- Q4035582 wikiPageWikiLink Q219567.
- Q4035582 wikiPageWikiLink Q223143.
- Q4035582 wikiPageWikiLink Q417823.
- Q4035582 wikiPageWikiLink Q430258.
- Q4035582 wikiPageWikiLink Q6005558.
- Q4035582 wikiPageWikiLink Q7187.
- Q4035582 wikiPageWikiLink Q79448.
- Q4035582 wikiPageWikiLink Q79460.
- Q4035582 wikiPageWikiLink Q899107.
- Q4035582 wikiPageWikiLink Q899790.
- Q4035582 wikiPageWikiLink Q9016234.
- Q4035582 arm "p".
- Q4035582 arm "q".
- Q4035582 band "11.2".
- Q4035582 band "21.1".
- Q4035582 band "21.2".
- Q4035582 chromosome "1".
- Q4035582 entrezgene "2209".
- Q4035582 entrezgene "2210".
- Q4035582 entrezgene "2211".
- Q4035582 hgncid "3613".
- Q4035582 hgncid "3614".
- Q4035582 hgncid "3615".
- Q4035582 locussupplementarydata "-21.3".
- Q4035582 name Q17927763.
- Q4035582 name "Fc fragment of IgG, high affinity Ib, receptor".
- Q4035582 name "Fc fragment of IgG, high affinity Ic, receptor".
- Q4035582 omim "146760".
- Q4035582 omim "601502".
- Q4035582 omim "601503".
- Q4035582 refseq "NM_000566".
- Q4035582 refseq "NM_001004340".
- Q4035582 refseq "XM_001133198".
- Q4035582 symbol "FCGR1A".
- Q4035582 symbol "FCGR1B".
- Q4035582 symbol "FCGR1C".
- Q4035582 uniprot "P12314".
- Q4035582 uniprot "Q92637".
- Q4035582 type Biomolecule.
- Q4035582 type Protein.
- Q4035582 type Thing.
- Q4035582 type Q206229.
- Q4035582 type Q8054.
- Q4035582 comment "CD64 (Cluster of Differentiation 64) is a type of integral membrane glycoprotein known as an Fc receptor that binds monomeric IgG-type antibodies with high affinity. It is more commonly known as Fc-gamma receptor 1 (FcγRI).".
- Q4035582 label "CD64 (biology)".
- Q4035582 name "Fc fragment of IgG, high affinity Ia, receptor (CD64)".
- Q4035582 name "Fc fragment of IgG, high affinity Ib, receptor (CD64)".
- Q4035582 name "Fc fragment of IgG, high affinity Ic, receptor (CD64)".