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- Q3982536 subject Q6994655.
- Q3982536 subject Q8788410.
- Q3982536 abstract "Tedisamil (3,7-dicyclopropylmethyl-9,9-tetramethylene-3,7-diazabicyclo-3,3,1-nonane) is an experimental class III antiarrhythmic agent currently being investigated for the treatment of atrial fibrillation. Tedisamil blocks multiple types of potassium channels in the heart resulting in slowed heart rate. While the effects of tedisamil have been demonstrated in both atrial and ventricular muscle, repolarization is prolonged more efficiently in the atria. Tedisamil is administered intravenously and has a half-life of approximately 8 –13 hours in circulation. Tedisamil is being developed as an alternative to other antiarrhythmics as incidence of additional arrhythmic events is lower compared to other class III agents. Tedisamil also has significant anti-ischemic properties and was initially investigated as a potential treatment for angina until its antiarrhythmic effects were discovered.Tedisamil is manufactured by Solvay Pharmaceuticals Inc. under the proposed trade name Pulzium and is currently in phase III of clinical testing for atrial fibrillation.".
- Q3982536 atcPrefix "C01".
- Q3982536 atcSuffix "BD06".
- Q3982536 casNumber "90961-53-8".
- Q3982536 fdaUniiCode "A5VAY2U3R8".
- Q3982536 iupacName "3,7-bis(cyclopropylmethyl)-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,1'-cyclopentane]".
- Q3982536 pubchem "65825".
- Q3982536 thumbnail Tedisamil.svg?width=300.
- Q3982536 wikiPageWikiLink Q189331.
- Q3982536 wikiPageWikiLink Q194277.
- Q3982536 wikiPageWikiLink Q241549.
- Q3982536 wikiPageWikiLink Q286020.
- Q3982536 wikiPageWikiLink Q423778.
- Q3982536 wikiPageWikiLink Q47270.
- Q3982536 wikiPageWikiLink Q6994655.
- Q3982536 wikiPageWikiLink Q815819.
- Q3982536 wikiPageWikiLink Q8788410.
- Q3982536 atcPrefix "1.0".
- Q3982536 atcSuffix "BD06".
- Q3982536 casNumber "90961".
- Q3982536 iupacName "37".
- Q3982536 pubchem "65825".
- Q3982536 unii "A5VAY2U3R8".
- Q3982536 type ChemicalSubstance.
- Q3982536 type Drug.
- Q3982536 type ChemicalObject.
- Q3982536 type Thing.
- Q3982536 type Q8386.
- Q3982536 comment "Tedisamil (3,7-dicyclopropylmethyl-9,9-tetramethylene-3,7-diazabicyclo-3,3,1-nonane) is an experimental class III antiarrhythmic agent currently being investigated for the treatment of atrial fibrillation. Tedisamil blocks multiple types of potassium channels in the heart resulting in slowed heart rate. While the effects of tedisamil have been demonstrated in both atrial and ventricular muscle, repolarization is prolonged more efficiently in the atria.".
- Q3982536 label "Tedisamil".
- Q3982536 depiction Tedisamil.svg.