Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q3976827> ?p ?o }
Showing triples 1 to 46 of
46
with 100 triples per page.
- Q3976827 subject Q7335370.
- Q3976827 subject Q8824848.
- Q3976827 abstract "Sulfapyridine, original UK spelling sulphapyridine, is a sulfonamide antibacterial. At one time it was commonly referred to as M&B.Sulfapyridine is no longer prescribed for treatment of infections in humans. However, it may be used to treat linear IgA disease. It is a good antibacterial drug, but its water solubility is very pH dependent. Thus there is a risk of crystallization within the bladder or urethra, which could lead to pain or blockage. As with other sulfonamides, there is a significant risk of agranulocytosis, and this, rather than the development of resistance by bacteria, is the main reason for its decline in use.It was discovered by Lionel Whitby at the British firm May & Baker Ltd and logged in their Test Book on 2 November, 1937 under Code No M&B 693. It was successfully used to treat Winston Churchill's bacterial pneumonia in 1942. In a subsequent radio broadcast he said: "This admirable M&B from which I did not suffer any inconvenience, was used at the earliest moment and, after a week's fever, the intruders were repulsed."In 1944 M&B 693 also saved Nero, the Royal Circus lion, from pneumonia. [Glasgow Evening News January 1944.]The drug sulfasalazine is structurally one molecule of mesalamine linked to one molecule of sulfapyridine with an azo bond.M&B 693 was one of the first generation of sulphonamide antibiotics. It has been reported as the first chemical cure for pneumonia. It could either be taken in tablet form or the powder could be placed in wounds. It was used so widely during the Second World War that May & Baker had difficulty keeping up with demand. It was later largely superseded by penicillin and other sulfonamides.".
- Q3976827 atcPrefix "J01".
- Q3976827 atcSuffix "EB04".
- Q3976827 casNumber "144-83-2".
- Q3976827 chEBI "132842".
- Q3976827 drugbank "DB00891".
- Q3976827 fdaUniiCode "Y5V2N1KE8U".
- Q3976827 iupacName "4-amino-N-pyridin-2-ylbenzenesulfonamide".
- Q3976827 pubchem "5336".
- Q3976827 thumbnail Sulfapyridine.png?width=300.
- Q3976827 wikiPageWikiLink Q12187.
- Q3976827 wikiPageWikiLink Q12190.
- Q3976827 wikiPageWikiLink Q16750630.
- Q3976827 wikiPageWikiLink Q170731.
- Q3976827 wikiPageWikiLink Q284256.
- Q3976827 wikiPageWikiLink Q396013.
- Q3976827 wikiPageWikiLink Q40936.
- Q3976827 wikiPageWikiLink Q411398.
- Q3976827 wikiPageWikiLink Q412479.
- Q3976827 wikiPageWikiLink Q420035.
- Q3976827 wikiPageWikiLink Q5.
- Q3976827 wikiPageWikiLink Q5405504.
- Q3976827 wikiPageWikiLink Q6796231.
- Q3976827 wikiPageWikiLink Q7335370.
- Q3976827 wikiPageWikiLink Q8016.
- Q3976827 wikiPageWikiLink Q8824848.
- Q3976827 wikiPageWikiLink Q9382.
- Q3976827 wikiPageWikiLink Q9386.
- Q3976827 atcPrefix "J01".
- Q3976827 atcSuffix "EB04".
- Q3976827 casNumber "144".
- Q3976827 chebi "132842".
- Q3976827 drugbank "DB00891".
- Q3976827 iupacName "4".
- Q3976827 pubchem "5336".
- Q3976827 unii "Y5V2N1KE8U".
- Q3976827 type ChemicalSubstance.
- Q3976827 type Drug.
- Q3976827 type ChemicalObject.
- Q3976827 type Thing.
- Q3976827 type Q8386.
- Q3976827 comment "Sulfapyridine, original UK spelling sulphapyridine, is a sulfonamide antibacterial. At one time it was commonly referred to as M&B.Sulfapyridine is no longer prescribed for treatment of infections in humans. However, it may be used to treat linear IgA disease. It is a good antibacterial drug, but its water solubility is very pH dependent. Thus there is a risk of crystallization within the bladder or urethra, which could lead to pain or blockage.".
- Q3976827 label "Sulfapyridine".
- Q3976827 depiction Sulfapyridine.png.