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- Q3597994 subject Q8395686.
- Q3597994 abstract "2,4 Dienoyl-CoA reductase also known as DECR1 is a protein which in humans is encoded by the DECR1 gene which resides on chromosome 8.This gene encodes an accessory enzyme that participates in the beta oxidation and metabolism of polyunsaturated fatty enoyl-CoA esters. Specifically, it catalyzes the reduction of 2,4 Dienoyl-CoA thioesters of varying length by NADPH cofactor to 3-trans-enoyl-CoA of equivalent length. Unlike the breakdown of saturated fat, cis and trans polyunsaturated fatty acid degradation requires three additional enzymes to generate a product compatible with the standard beta oxidation pathway. DECR is the second such enzyme (The others being Enoyl CoA isomerase and Dienoyl CoA isomerase) and is the rate limiting step in this auxiliary flow. DECR is capable of reducing both 2-trans,4-cis-dienoyl-CoA and 2-trans,4-trans-dienoyl-CoA thioesters, as well as double bonds at odd carbon positions, with equal efficiency. At this time, there is no clear explanation for this of lack of stereo-specificity.".
- Q3597994 arm "q".
- Q3597994 band "21.3".
- Q3597994 chromosome "8".
- Q3597994 ecNumber "1.3.1.34".
- Q3597994 entrezgene "1666".
- Q3597994 hgncid "2753".
- Q3597994 omim "222745".
- Q3597994 pdb "1w6u".
- Q3597994 refseq "NM_001359".
- Q3597994 symbol "DECR".
- Q3597994 symbol "DECR1".
- Q3597994 thumbnail DHFR.png?width=300.
- Q3597994 uniprot "Q16698".
- Q3597994 wikiPageWikiLink Q11321452.
- Q3597994 wikiPageWikiLink Q1364740.
- Q3597994 wikiPageWikiLink Q138639.
- Q3597994 wikiPageWikiLink Q1469559.
- Q3597994 wikiPageWikiLink Q1527480.
- Q3597994 wikiPageWikiLink Q1773248.
- Q3597994 wikiPageWikiLink Q178430.
- Q3597994 wikiPageWikiLink Q178450.
- Q3597994 wikiPageWikiLink Q18037983.
- Q3597994 wikiPageWikiLink Q183290.
- Q3597994 wikiPageWikiLink Q188017.
- Q3597994 wikiPageWikiLink Q207688.
- Q3597994 wikiPageWikiLink Q2294.
- Q3597994 wikiPageWikiLink Q25419.
- Q3597994 wikiPageWikiLink Q2698455.
- Q3597994 wikiPageWikiLink Q283611.
- Q3597994 wikiPageWikiLink Q28746.
- Q3597994 wikiPageWikiLink Q28747.
- Q3597994 wikiPageWikiLink Q306213.
- Q3597994 wikiPageWikiLink Q312085.
- Q3597994 wikiPageWikiLink Q3589012.
- Q3597994 wikiPageWikiLink Q373027.
- Q3597994 wikiPageWikiLink Q376061.
- Q3597994 wikiPageWikiLink Q39572.
- Q3597994 wikiPageWikiLink Q407426.
- Q3597994 wikiPageWikiLink Q407635.
- Q3597994 wikiPageWikiLink Q412366.
- Q3597994 wikiPageWikiLink Q418650.
- Q3597994 wikiPageWikiLink Q4596783.
- Q3597994 wikiPageWikiLink Q53833.
- Q3597994 wikiPageWikiLink Q556036.
- Q3597994 wikiPageWikiLink Q572848.
- Q3597994 wikiPageWikiLink Q7187.
- Q3597994 wikiPageWikiLink Q7702931.
- Q3597994 wikiPageWikiLink Q8054.
- Q3597994 wikiPageWikiLink Q8066.
- Q3597994 wikiPageWikiLink Q82264.
- Q3597994 wikiPageWikiLink Q826582.
- Q3597994 wikiPageWikiLink Q8395686.
- Q3597994 wikiPageWikiLink Q898362.
- Q3597994 wikiPageWikiLink Q907446.
- Q3597994 altsymbols "DECR".
- Q3597994 arm "q".
- Q3597994 band "21.3".
- Q3597994 chromosome "8".
- Q3597994 ecnumber "1.3".
- Q3597994 entrezgene "1666".
- Q3597994 hgncid "2753".
- Q3597994 name "24".
- Q3597994 omim "222745".
- Q3597994 pdb "1".
- Q3597994 refseq "NM_001359".
- Q3597994 symbol "DECR1".
- Q3597994 uniprot "Q16698".
- Q3597994 type Biomolecule.
- Q3597994 type Protein.
- Q3597994 type Thing.
- Q3597994 type Q206229.
- Q3597994 type Q8054.
- Q3597994 comment "2,4 Dienoyl-CoA reductase also known as DECR1 is a protein which in humans is encoded by the DECR1 gene which resides on chromosome 8.This gene encodes an accessory enzyme that participates in the beta oxidation and metabolism of polyunsaturated fatty enoyl-CoA esters. Specifically, it catalyzes the reduction of 2,4 Dienoyl-CoA thioesters of varying length by NADPH cofactor to 3-trans-enoyl-CoA of equivalent length.".
- Q3597994 label "2,4 Dienoyl-CoA reductase".
- Q3597994 depiction DHFR.png.
- Q3597994 name "2,4-dienoyl CoA reductase 1, mitochondrial".