Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q335099> ?p ?o }
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- Q335099 subject Q7158320.
- Q335099 subject Q7441579.
- Q335099 subject Q7486806.
- Q335099 subject Q8672733.
- Q335099 subject Q9194603.
- Q335099 abstract "Edaravone (brand name ラジカット, Radicut) is a nootropic and neuroprotective agent used for the purpose of aiding neurological recovery following acute brain ischemia and subsequent cerebral infarction. It acts as a potent antioxidant and strongly scavenges free radicals, protecting against oxidative stress and neuronal apoptosis. It has been marketed solely in Japan by Mitsubishi Pharma since 2001. It is also marketed in India by Edinburgh Pharmaceuticals by the brand name Arone.On June 26th, 2015, Mitsubishi Tanabe Pharma Corporation announced it has received approval to market Radicut for treatment of ALS in Japan. The phase III clinical trial began in 2011 in Japan. The company was awarded Orphan Drug Designation for Radicut by the FDA and EU in 2015. Radicut is an intravenous drug and administrated 14 days followed by 14 days drug holiday.The biotech company Treeway is developing an oral formulation of edaravone (TW001) and is currently in clinical development. Treeway was awarded orphan drug designation for edaravone by the EMA in November 2014 and FDA in January 2015.Edaravone has been shown to attenuate methamphetamine- and 6-OHDA-induced dopaminergic neurotoxicity in the striatum and substantia nigra, and does not affect methamphetamine-induced dopamine release or hyperthermia. It has also been demonstrated to protect against MPTP-mediated dopaminergic neurotoxicity to the substantia nigra, though notably not to the striatum.".
- Q335099 atcPrefix "none".
- Q335099 casNumber "89-25-8".
- Q335099 chEBI "31530".
- Q335099 fdaUniiCode "S798V6YJRP".
- Q335099 iupacName "5-methyl-2-phenyl-4H-pyrazol-3-one".
- Q335099 pubchem "4021".
- Q335099 thumbnail Edaravone.svg?width=300.
- Q335099 wikiPageExternalLink 21678421.2014.959024.
- Q335099 wikiPageExternalLink 168.
- Q335099 wikiPageExternalLink radicut-approved-for-als-in-japan.
- Q335099 wikiPageExternalLink e_MTPC150626_2.pdf.
- Q335099 wikiPageWikiLink Q10681911.
- Q335099 wikiPageWikiLink Q1209150.
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- Q335099 wikiPageWikiLink Q4862390.
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- Q335099 wikiPageWikiLink Q6883161.
- Q335099 wikiPageWikiLink Q7158320.
- Q335099 wikiPageWikiLink Q742487.
- Q335099 wikiPageWikiLink Q7441579.
- Q335099 wikiPageWikiLink Q7486806.
- Q335099 wikiPageWikiLink Q753278.
- Q335099 wikiPageWikiLink Q780181.
- Q335099 wikiPageWikiLink Q83042.
- Q335099 wikiPageWikiLink Q8386.
- Q335099 wikiPageWikiLink Q8672733.
- Q335099 wikiPageWikiLink Q898814.
- Q335099 wikiPageWikiLink Q9194603.
- Q335099 atcPrefix "none".
- Q335099 casNumber "89".
- Q335099 chebi "31530".
- Q335099 iupacName "5".
- Q335099 pubchem "4021".
- Q335099 unii "S798V6YJRP".
- Q335099 type ChemicalSubstance.
- Q335099 type Drug.
- Q335099 type ChemicalObject.
- Q335099 type Thing.
- Q335099 type Q8386.
- Q335099 comment "Edaravone (brand name ラジカット, Radicut) is a nootropic and neuroprotective agent used for the purpose of aiding neurological recovery following acute brain ischemia and subsequent cerebral infarction. It acts as a potent antioxidant and strongly scavenges free radicals, protecting against oxidative stress and neuronal apoptosis. It has been marketed solely in Japan by Mitsubishi Pharma since 2001.".
- Q335099 label "Edaravone".
- Q335099 depiction Edaravone.svg.