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- Q3270742 subject Q8384960.
- Q3270742 subject Q8949762.
- Q3270742 abstract "Prostratin is a protein kinase C activator found in the bark of the mamala tree of Samoa, Homalanthus nutans (Euphorbiaceae). While prostratin was originally isolated and identified as a new phorbol from species of the genus Pimelea (Thymelaceae) in Australia, the antiviral activity of prostratin was discovered during research on the traditional knowledge of Samoan healers in Falealupo village by ethnobotanist Paul Alan Cox and a team at the U.S. National Cancer Institute. Samoan healers use the mamala tree to treat hepatitis. Research indicated that prostratin has potential to be useful in the treatment of HIV as it could flush viral reservoirs in latently infected CD4+ T-cells.As a modulator of Protein Kinase C, it has been shown to exhibit promising therapeutic potential against other diseases such as cancer and Alzheimer's disease. In 2015, study showed that orally administrated prostratin repressed human pancreatic tumor.".
- Q3270742 iupacName "(1aR,1bS,4aR,7aS,7bR,8R,9aS)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl acetate".
- Q3270742 thumbnail Prostratin.svg?width=300.
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- Q3270742 wikiPageExternalLink samoa.htm.
- Q3270742 wikiPageExternalLink samoahiv-050708.html.
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- Q3270742 wikiPageExternalLink prweb3532854.htm.
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- Q3270742 wikiPageWikiLink Q683.
- Q3270742 wikiPageWikiLink Q8384960.
- Q3270742 wikiPageWikiLink Q841408.
- Q3270742 wikiPageWikiLink Q8949762.
- Q3270742 iupacname "-4".
- Q3270742 type ChemicalCompound.
- Q3270742 type ChemicalSubstance.
- Q3270742 type ChemicalObject.
- Q3270742 type Thing.
- Q3270742 type Q11173.
- Q3270742 comment "Prostratin is a protein kinase C activator found in the bark of the mamala tree of Samoa, Homalanthus nutans (Euphorbiaceae). While prostratin was originally isolated and identified as a new phorbol from species of the genus Pimelea (Thymelaceae) in Australia, the antiviral activity of prostratin was discovered during research on the traditional knowledge of Samoan healers in Falealupo village by ethnobotanist Paul Alan Cox and a team at the U.S. National Cancer Institute.".
- Q3270742 label "Prostratin".
- Q3270742 depiction Prostratin.svg.