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- Q3073444 subject Q8226501.
- Q3073444 subject Q8297708.
- Q3073444 abstract "Flavaglines are a family of natural products that are found in plants of the genus Aglaia (Meliaceae). These compounds are characterized by a cyclopenta[b]benzofuran skeleton. In 1982 King and colleagues discovered the first member of this family, rocaglamide, based on its antileukemic activity. Since then, about 50 other flavaglines have been characterized. These molecules display strong insecticidal, antifungal, anti-inflammatory, neuroprotective, cardioprotective and anticancer activities. In mouse models of cancer, flavaglines enhance the efficacy of chemotherapies and also alleviate the cardiac adverse effect of these chemotherapies.The challenge raised by their structural complexity has attracted the attention of some organic chemists. In 1990, Barry Trost presented an enantioselective synthesis of rocaglamide in 18 steps and confirmed its absolute configuration.".
- Q3073444 thumbnail Flavagline_FL3.svg?width=300.
- Q3073444 wikiPageWikiLink Q158979.
- Q3073444 wikiPageWikiLink Q3063295.
- Q3073444 wikiPageWikiLink Q3437403.
- Q3073444 wikiPageWikiLink Q410089.
- Q3073444 wikiPageWikiLink Q4774590.
- Q3073444 wikiPageWikiLink Q494483.
- Q3073444 wikiPageWikiLink Q725840.
- Q3073444 wikiPageWikiLink Q734343.
- Q3073444 wikiPageWikiLink Q8226501.
- Q3073444 wikiPageWikiLink Q8297708.
- Q3073444 comment "Flavaglines are a family of natural products that are found in plants of the genus Aglaia (Meliaceae). These compounds are characterized by a cyclopenta[b]benzofuran skeleton. In 1982 King and colleagues discovered the first member of this family, rocaglamide, based on its antileukemic activity. Since then, about 50 other flavaglines have been characterized. These molecules display strong insecticidal, antifungal, anti-inflammatory, neuroprotective, cardioprotective and anticancer activities.".
- Q3073444 label "Flavagline".
- Q3073444 depiction Flavagline_FL3.svg.