Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q290671> ?p ?o }
Showing triples 1 to 41 of
41
with 100 triples per page.
- Q290671 subject Q7211373.
- Q290671 abstract "A single-chain variable fragment (scFv) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy (VH) and light chains (VL) of immunoglobulins, connected with a short linker peptide of ten to about 25 amino acids. The linker is usually rich in glycine for flexibility, as well as serine or threonine for solubility, and can either connect the N-terminus of the VH with the C-terminus of the VL, or vice versa.This protein retains the specificity of the original immunoglobulin, despite removal of the constant regions and the introduction of the linker. The image to the right shows how this modification usually leaves the specificity unaltered.These molecules were created to facilitate phage display, where it is highly convenient to express the antigen-binding domain as a single peptide. As an alternative, scFv can be created directly from subcloned heavy and light chains derived from a hybridoma. ScFvs have many uses, e.g., flow cytometry, immunohistochemistry, and as antigen-binding domains of artificial T cell receptors.Unlike monoclonal antibodies, which are often produced in mammalian cell cultures, scFvs are more often produced in bacteria cell cultures such as E. coli.".
- Q290671 thumbnail ScFv-rotation.gif?width=300.
- Q290671 wikiPageWikiLink Q1141429.
- Q290671 wikiPageWikiLink Q128581.
- Q290671 wikiPageWikiLink Q14877486.
- Q290671 wikiPageWikiLink Q14905306.
- Q290671 wikiPageWikiLink Q1616930.
- Q290671 wikiPageWikiLink Q172847.
- Q290671 wikiPageWikiLink Q183290.
- Q290671 wikiPageWikiLink Q186521.
- Q290671 wikiPageWikiLink Q235007.
- Q290671 wikiPageWikiLink Q25419.
- Q290671 wikiPageWikiLink Q284398.
- Q290671 wikiPageWikiLink Q310425.
- Q290671 wikiPageWikiLink Q334848.
- Q290671 wikiPageWikiLink Q3776943.
- Q290671 wikiPageWikiLink Q4115252.
- Q290671 wikiPageWikiLink Q422248.
- Q290671 wikiPageWikiLink Q424403.
- Q290671 wikiPageWikiLink Q425158.
- Q290671 wikiPageWikiLink Q425941.
- Q290671 wikiPageWikiLink Q426141.
- Q290671 wikiPageWikiLink Q5099363.
- Q290671 wikiPageWikiLink Q620730.
- Q290671 wikiPageWikiLink Q7179565.
- Q290671 wikiPageWikiLink Q7211373.
- Q290671 wikiPageWikiLink Q7251440.
- Q290671 wikiPageWikiLink Q79460.
- Q290671 wikiPageWikiLink Q8066.
- Q290671 wikiPageWikiLink Q855177.
- Q290671 wikiPageWikiLink Q896217.
- Q290671 wikiPageWikiLink Q898254.
- Q290671 wikiPageWikiLink Q899107.
- Q290671 wikiPageWikiLink Q899285.
- Q290671 wikiPageWikiLink Q909628.
- Q290671 wikiPageWikiLink Q949267.
- Q290671 wikiPageWikiLink Q978273.
- Q290671 comment "A single-chain variable fragment (scFv) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy (VH) and light chains (VL) of immunoglobulins, connected with a short linker peptide of ten to about 25 amino acids.".
- Q290671 label "Single-chain variable fragment".
- Q290671 depiction ScFv-rotation.gif.