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- Q2732398 subject Q6853449.
- Q2732398 subject Q6853484.
- Q2732398 subject Q7215462.
- Q2732398 subject Q8346785.
- Q2732398 abstract "Autosomal dominant polycystic kidney disease (ADPKD, autosomal dominant PKD or adult-onset PKD) is the most prevalent, potentially lethal, monogenic human disorder. It is associated with large interfamilial and intrafamilial variability, which can be explained to a large extent by its genetic heterogeneity and modifier genes. It is also the most common of the inherited cystic kidney diseases — a group of disorders with related but distinct pathogenesis, characterized by the development of renal cysts and various extrarenal manifestations, which in case of ADPKD include cysts in other organs, such as the liver, seminal vesicles, pancreas, and arachnoid membrane, as well as other abnormalities, such as intracranial aneurysms and dolichoectasias, aortic root dilatation and aneurysms, mitral valve prolapse, and abdominal wall hernias. Over 50% of patients with ADPKD eventually develop end stage kidney disease and require dialysis or kidney transplantation. ADPKD is estimated to affect at least 1 in every 1000 individuals worldwide, making this disease the most common inherited kidney disorder with a diagnosed prevalence of 1:2000 and incidence of 1:3000-1:8000 in a global scale.".
- Q2732398 icd10 "Q61".
- Q2732398 icd9 "753.1".
- Q2732398 meshId "D016891".
- Q2732398 omim "601313".
- Q2732398 thumbnail Polycystic_kidneys,_gross_pathology_20G0027_lores.jpg?width=300.
- Q2732398 wikiPageExternalLink index.htm.
- Q2732398 wikiPageExternalLink PKD.html.
- Q2732398 wikiPageExternalLink www.pkdcure.org.
- Q2732398 wikiPageExternalLink a07fig06.jpg.
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- Q2732398 icd "753.1".
- Q2732398 icd "Q61".
- Q2732398 meshid "D016891".
- Q2732398 name "Polycystic Kidney Disease".
- Q2732398 omim "601313".
- Q2732398 type Disease.
- Q2732398 type Thing.
- Q2732398 type Q12136.
- Q2732398 comment "Autosomal dominant polycystic kidney disease (ADPKD, autosomal dominant PKD or adult-onset PKD) is the most prevalent, potentially lethal, monogenic human disorder. It is associated with large interfamilial and intrafamilial variability, which can be explained to a large extent by its genetic heterogeneity and modifier genes.".
- Q2732398 label "Autosomal dominant polycystic kidney disease".
- Q2732398 depiction Polycystic_kidneys,_gross_pathology_20G0027_lores.jpg.
- Q2732398 name "Polycystic Kidney Disease".