Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q2650256> ?p ?o }
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- Q2650256 subject Q19978189.
- Q2650256 subject Q5856563.
- Q2650256 subject Q7334131.
- Q2650256 subject Q7334142.
- Q2650256 subject Q7335338.
- Q2650256 subject Q8281823.
- Q2650256 subject Q8493005.
- Q2650256 subject Q8790228.
- Q2650256 abstract "Gepirone (INN) (developmental code names BMY-13805, MJ-13805, ORG-13011, TGFK07AD; proposed brand names Ariza, Variza) or gepirone hydrochloride (USAN) is an antidepressant and anxiolytic drug of the azapirone group that has never been marketed. Like other azapirones, it acts as a selective partial agonist of the 5-HT1A receptor. Gepirone was under development in the U.S. in an extended release form, but despite completing phase III clinical trials, it failed to pass the drug approval process. As a result, gepirone, despite already having brand names chosen, did not manage to reach the pharmaceutical market.Gepirone was originally developed by Bristol-Myers Squibb, but was out-licensed to Fabre-Kramer in 1993. The U.S. Food and Drug Administration (FDA) rejected approval for gepirone in 2004. It was submitted for the preregistration (NDA) phase again in May 2007 after adding additional information from clinical trials as the FDA required in 2004. However, in 2007 it once again failed to convince the FDA of its qualities for treating anxiety and depression. In December 2015, the FDA once again gave gepirone a negative review for depression due to concerns of efficacy.[1]".
- Q2650256 atcPrefix "N06".
- Q2650256 atcSuffix "AX19".
- Q2650256 casNumber "83928-76-1".
- Q2650256 fdaUniiCode "JW5Y7B8Z18".
- Q2650256 iupacName "4,4-Dimethyl-1-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]piperidine-2,6-dione".
- Q2650256 pubchem "55191".
- Q2650256 thumbnail Gepirone.svg?width=300.
- Q2650256 wikiPageExternalLink 800000684.
- Q2650256 wikiPageWikiLink Q1756385.
- Q2650256 wikiPageWikiLink Q19978189.
- Q2650256 wikiPageWikiLink Q204711.
- Q2650256 wikiPageWikiLink Q2198549.
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- Q2650256 wikiPageWikiLink Q266423.
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- Q2650256 wikiPageWikiLink Q5856563.
- Q2650256 wikiPageWikiLink Q6151362.
- Q2650256 wikiPageWikiLink Q62903.
- Q2650256 wikiPageWikiLink Q7180990.
- Q2650256 wikiPageWikiLink Q718608.
- Q2650256 wikiPageWikiLink Q7334131.
- Q2650256 wikiPageWikiLink Q7334142.
- Q2650256 wikiPageWikiLink Q7335338.
- Q2650256 wikiPageWikiLink Q76560.
- Q2650256 wikiPageWikiLink Q770260.
- Q2650256 wikiPageWikiLink Q824258.
- Q2650256 wikiPageWikiLink Q8281823.
- Q2650256 wikiPageWikiLink Q8386.
- Q2650256 wikiPageWikiLink Q8493005.
- Q2650256 wikiPageWikiLink Q8790228.
- Q2650256 atcPrefix "N06".
- Q2650256 atcSuffix "AX19".
- Q2650256 casNumber "83928".
- Q2650256 iupacName "44".
- Q2650256 pubchem "55191".
- Q2650256 unii "JW5Y7B8Z18".
- Q2650256 type ChemicalSubstance.
- Q2650256 type Drug.
- Q2650256 type ChemicalObject.
- Q2650256 type Thing.
- Q2650256 type Q8386.
- Q2650256 comment "Gepirone (INN) (developmental code names BMY-13805, MJ-13805, ORG-13011, TGFK07AD; proposed brand names Ariza, Variza) or gepirone hydrochloride (USAN) is an antidepressant and anxiolytic drug of the azapirone group that has never been marketed. Like other azapirones, it acts as a selective partial agonist of the 5-HT1A receptor. Gepirone was under development in the U.S. in an extended release form, but despite completing phase III clinical trials, it failed to pass the drug approval process.".
- Q2650256 label "Gepirone".
- Q2650256 depiction Gepirone.svg.