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- Q263609 subject Q6853484.
- Q263609 subject Q8367854.
- Q263609 abstract "Pemphigus foliaceus is an autoimmune blistering disease of the skin with characteristic lesions that are scaly, crusted erosions, often on an erythematous base. Mucosal involvement is absent even with widespread disease.If there is an autoimmune IgG buildup in the epidermis, then nearly almost all of the antibodies are aimed against desmoglein 1. The effect of the antibodies and the immunological pathway is most likely either of three mechanisms: Steric hindrance of the desmoglein 1: The antibody caps off the site for intracellular binding to another keratinocyte. Activation of an endocytic pathway: The antibody activates a pathway which causes an internalization of desmogleïn 1, which in turn causes a loss of adhesion. Disruption of function: In this case, the antibody blocks the desmoglein 1 from being formed into a desmosome. This in turn causes a loss of adhesion with acantholysis as a result.↑ ↑".
- Q263609 icd10 "L10.2".
- Q263609 wikiPageWikiLink Q123452.
- Q263609 wikiPageWikiLink Q1483214.
- Q263609 wikiPageWikiLink Q18022939.
- Q263609 wikiPageWikiLink Q212743.
- Q263609 wikiPageWikiLink Q246809.
- Q263609 wikiPageWikiLink Q6853484.
- Q263609 wikiPageWikiLink Q6973606.
- Q263609 wikiPageWikiLink Q79448.
- Q263609 wikiPageWikiLink Q8367854.
- Q263609 icd "L10.2".
- Q263609 name "Pemphigus foliaceus".
- Q263609 type Disease.
- Q263609 type Thing.
- Q263609 type Q12136.
- Q263609 comment "Pemphigus foliaceus is an autoimmune blistering disease of the skin with characteristic lesions that are scaly, crusted erosions, often on an erythematous base. Mucosal involvement is absent even with widespread disease.If there is an autoimmune IgG buildup in the epidermis, then nearly almost all of the antibodies are aimed against desmoglein 1.".
- Q263609 label "Pemphigus foliaceus".
- Q263609 name "Pemphigus foliaceus".