Matches in DBpedia 2016-04 for { <http://wikidata.dbpedia.org/resource/Q261968> ?p ?o }
- Q261968 subject Q8395597.
- Q261968 subject Q8420225.
- Q261968 subject Q8660667.
- Q261968 subject Q8660670.
- Q261968 abstract "Isocitrate dehydrogenase (IDH) (EC 1.1.1.42) and (EC 1.1.1.41) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2. This is a two-step process, which involves oxidation of isocitrate (a secondary alcohol) to oxalosuccinate (a ketone), followed by the decarboxylation of the carboxyl group beta to the ketone, forming alpha-ketoglutarate. In humans, IDH exists in three isoforms: IDH3 catalyzes the third step of the citric acid cycle while converting NAD+ to NADH in the mitochondria. The isoforms IDH1 and IDH2 catalyze the same reaction outside the context of the citric acid cycle and use NADP+ as a cofactor instead of NAD+. They localize to the cytosol as well as the mitochondrion and peroxisome.".
- Q261968 ecNumber "1.1.1.41".
- Q261968 ecNumber "1.1.1.42".
- Q261968 thumbnail Isocitrate_dehydrogenase_of_Escherichia_coli_Complex.jpg?width=300.
- Q261968 wikiPageExternalLink motm.do?momID=129.
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- Q261968 arm "p".
- Q261968 arm "q".
- Q261968 band "13".
- Q261968 band "21".
- Q261968 band "25.1".
- Q261968 band "28".
- Q261968 band "32".
- Q261968 chromosome "15".
- Q261968 chromosome "2".
- Q261968 chromosome "20".
- Q261968 chromosome "X".
- Q261968 ecNumber "1.1".
- Q261968 ecnumber "1.1".
- Q261968 entrezgene "3417".
- Q261968 entrezgene "3418".
- Q261968 entrezgene "3419".
- Q261968 entrezgene "3420".
- Q261968 entrezgene "3421".
- Q261968 hgncid "5382".
- Q261968 hgncid "5383".
- Q261968 hgncid "5384".
- Q261968 hgncid "5385".
- Q261968 hgncid "5386".
- Q261968 locussupplementarydata "-25.2".
- Q261968 locussupplementarydata "-qter".
- Q261968 name "Isocitrate dehydrogenase".
- Q261968 name "isocitrate dehydrogenase 1 , soluble".
- Q261968 name "isocitrate dehydrogenase 2 , mitochondrial".
- Q261968 name "isocitrate dehydrogenase 3 alpha".
- Q261968 name "isocitrate dehydrogenase 3 beta".
- Q261968 name "isocitrate dehydrogenase 3 gamma".
- Q261968 name "isocitrate dehydrogenase".
- Q261968 omim "147650".
- Q261968 omim "147700".
- Q261968 omim "300089".
- Q261968 omim "601149".
- Q261968 omim "604526".
- Q261968 refseq "NM_002168".
- Q261968 refseq "NM_005530".
- Q261968 refseq "NM_005896".