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- Q261167 subject Q8808701.
- Q261167 subject Q9062284.
- Q261167 abstract "Ibudilast (development codes: AV-411 or MN-166) is an antiinflammatory drug used mainly in Japan, which acts as a phosphodiesterase inhibitor, inhibiting the PDE-4 subtype to the greatest extent, but also showing significant inhibition of other PDE subtypes.Ibudilast has bronchodilator, vasodilator and neuroprotective effects, and is mainly used in the treatment of asthma and stroke. It inhibits platelet aggregation, and may also be useful in the treatment of multiple sclerosis.Ibudilast crosses the blood–brain barrier and suppresses glial cell activation. This activity has been shown to make ibudilast useful in the treatment of neuropathic pain and it not only enhances analgesia produced by opioid drugs, but also reduces the development of tolerance.It may have some use reducing methamphetamine and alcohol addiction.".
- Q261167 atcPrefix "R03".
- Q261167 atcSuffix "DC04".
- Q261167 casNumber "50847-11-5".
- Q261167 drugbank "DB05266".
- Q261167 fdaUniiCode "M0TTH61XC5".
- Q261167 iupacName "2-methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one".
- Q261167 pubchem "3671".
- Q261167 thumbnail Ibudilast.svg?width=300.
- Q261167 wikiPageWikiLink Q101026.
- Q261167 wikiPageWikiLink Q12202.
- Q261167 wikiPageWikiLink Q1425425.
- Q261167 wikiPageWikiLink Q14859627.
- Q261167 wikiPageWikiLink Q173235.
- Q261167 wikiPageWikiLink Q177105.
- Q261167 wikiPageWikiLink Q1981368.
- Q261167 wikiPageWikiLink Q221694.
- Q261167 wikiPageWikiLink Q35869.
- Q261167 wikiPageWikiLink Q418251.
- Q261167 wikiPageWikiLink Q427523.
- Q261167 wikiPageWikiLink Q581996.
- Q261167 wikiPageWikiLink Q7825858.
- Q261167 wikiPageWikiLink Q8277.
- Q261167 wikiPageWikiLink Q8808701.
- Q261167 wikiPageWikiLink Q9062284.
- Q261167 wikiPageWikiLink Q927234.
- Q261167 atcPrefix "R03".
- Q261167 atcSuffix "DC04".
- Q261167 casNumber "50847".
- Q261167 drugbank "DB05266".
- Q261167 iupacName "2".
- Q261167 pubchem "3671".
- Q261167 unii "M0TTH61XC5".
- Q261167 type ChemicalSubstance.
- Q261167 type Drug.
- Q261167 type ChemicalObject.
- Q261167 type Thing.
- Q261167 type Q8386.
- Q261167 comment "Ibudilast (development codes: AV-411 or MN-166) is an antiinflammatory drug used mainly in Japan, which acts as a phosphodiesterase inhibitor, inhibiting the PDE-4 subtype to the greatest extent, but also showing significant inhibition of other PDE subtypes.Ibudilast has bronchodilator, vasodilator and neuroprotective effects, and is mainly used in the treatment of asthma and stroke.".
- Q261167 label "Ibudilast".
- Q261167 depiction Ibudilast.svg.