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- Q2581447 subject Q17579368.
- Q2581447 subject Q22902012.
- Q2581447 subject Q52359.
- Q2581447 subject Q7335338.
- Q2581447 subject Q7441579.
- Q2581447 subject Q8556383.
- Q2581447 subject Q8871842.
- Q2581447 subject Q9052268.
- Q2581447 abstract "Sulbutiamine (brand name: Arcalion) is a synthetic derivative of thiamine (vitamin B1). As a dimer of two modified thiamine molecules, it is a lipophilic compound that crosses the blood–brain barrier more readily than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain. Sulbutiamine was discovered in Japan in an effort to develop more useful thiamine derivatives since it was hoped that increasing the lipophilicity of thiamine would result in better pharmacokinetic properties.Although its clinical efficacy is uncertain, it is the only compound used to treat asthenia that is known to selectively target the areas that are involved in the condition. In addition to its use as a treatment for chronic fatigue, sulbutiamine may improve memory, reduce psycho-behavioural inhibition, and improve erectile dysfunction. At therapeutic dosages, it has few reported adverse effects. It is available for over-the-counter sale as a nutritional supplement.".
- Q2581447 atcPrefix "A11".
- Q2581447 atcSuffix "DA02".
- Q2581447 casNumber "3286-46-2".
- Q2581447 fdaUniiCode "42NCM1BW43".
- Q2581447 iupacName "[4-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-3-[2-[(4-amino-2-methyl-pyrimidin-5-yl)methyl-formyl-amino]-5-(2-methylpropanoyloxy)pent-2-en-3-yl]disulfanyl-pent-3-enyl] 2-methylpropanoate".
- Q2581447 pubchem "71124".
- Q2581447 thumbnail Sulbutiamine.svg?width=300.
- Q2581447 wikiPageWikiLink Q1154971.
- Q2581447 wikiPageWikiLink Q170304.
- Q2581447 wikiPageWikiLink Q17579368.
- Q2581447 wikiPageWikiLink Q18022883.
- Q2581447 wikiPageWikiLink Q181136.
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- Q2581447 wikiPageWikiLink Q184674.
- Q2581447 wikiPageWikiLink Q18680.
- Q2581447 wikiPageWikiLink Q221694.
- Q2581447 wikiPageWikiLink Q22902012.
- Q2581447 wikiPageWikiLink Q23400.
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- Q2581447 wikiPageWikiLink Q413426.
- Q2581447 wikiPageWikiLink Q416361.
- Q2581447 wikiPageWikiLink Q438528.
- Q2581447 wikiPageWikiLink Q461809.
- Q2581447 wikiPageWikiLink Q4732877.
- Q2581447 wikiPageWikiLink Q492.
- Q2581447 wikiPageWikiLink Q52359.
- Q2581447 wikiPageWikiLink Q531306.
- Q2581447 wikiPageWikiLink Q633403.
- Q2581447 wikiPageWikiLink Q7251493.
- Q2581447 wikiPageWikiLink Q7335338.
- Q2581447 wikiPageWikiLink Q7441579.
- Q2581447 wikiPageWikiLink Q7662055.
- Q2581447 wikiPageWikiLink Q7676423.
- Q2581447 wikiPageWikiLink Q83187.
- Q2581447 wikiPageWikiLink Q8556383.
- Q2581447 wikiPageWikiLink Q8871842.
- Q2581447 wikiPageWikiLink Q898401.
- Q2581447 wikiPageWikiLink Q9052268.
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- Q2581447 atcPrefix "A11".
- Q2581447 atcSuffix "DA02".
- Q2581447 casNumber "3286".
- Q2581447 iupacName "[4-[methyl-formyl-amino]-3-[2-[methyl-formyl-amino]-5-pent-2-en-3-yl]disulfanyl-pent-3-enyl] 2-methylpropanoate".
- Q2581447 pubchem "71124".
- Q2581447 unii "42".
- Q2581447 type ChemicalSubstance.
- Q2581447 type Drug.
- Q2581447 type ChemicalObject.
- Q2581447 type Thing.
- Q2581447 type Q8386.
- Q2581447 comment "Sulbutiamine (brand name: Arcalion) is a synthetic derivative of thiamine (vitamin B1). As a dimer of two modified thiamine molecules, it is a lipophilic compound that crosses the blood–brain barrier more readily than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain.".
- Q2581447 label "Sulbutiamine".
- Q2581447 depiction Sulbutiamine.svg.