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- Q2341200 subject Q8302171.
- Q2341200 subject Q8421244.
- Q2341200 abstract "Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce vertebral fractures, hyperparathyroidism, hypercalcemia in malignancy, multiple myeloma and fracture related pain because of its potent anti-inflammatory and analgesic effects shown as a reduction in inflammatory markers like IL-1β, IL-6, and TNF-alfa.An Italian study compared the analgesic effect of clodronic acid versus acetaminophen in rheumatic condition related pain. Study result show a reduction in pain in favor of clodronic acid that provided more analgesia than 3 grams/day of acetaminophen. Clodronate is also used in experimental medicine to selectively deplete macrophages.Clodronic acid is approved for human use in Canada and Australia, the United Kingdom, where it is marketed as Bonefos, Loron, Clodron and in Italy as Clasteon, Difosfonal, Osteostab and several generics. In other countries is prescribed as a bone resorption inhibitor and antihypercalcemic agent.".
- Q2341200 atcPrefix "M05".
- Q2341200 atcSuffix "BA02".
- Q2341200 casNumber "10596-23-3".
- Q2341200 chEBI "110423".
- Q2341200 drugbank "DB00720".
- Q2341200 fdaUniiCode "0813BZ6866".
- Q2341200 iupacName "(dichloro-phosphono-methyl)phosphonic acid".
- Q2341200 pubchem "25419".
- Q2341200 thumbnail Clodronic_acid.png?width=300.
- Q2341200 wikiPageWikiLink Q1569563.
- Q2341200 wikiPageWikiLink Q184204.
- Q2341200 wikiPageWikiLink Q3873439.
- Q2341200 wikiPageWikiLink Q412205.
- Q2341200 wikiPageWikiLink Q4926095.
- Q2341200 wikiPageWikiLink Q57055.
- Q2341200 wikiPageWikiLink Q824258.
- Q2341200 wikiPageWikiLink Q8302171.
- Q2341200 wikiPageWikiLink Q8421244.
- Q2341200 atcPrefix "M05".
- Q2341200 atcSuffix "BA02".
- Q2341200 casNumber "10596".
- Q2341200 chebi "110423".
- Q2341200 drugbank "DB00720".
- Q2341200 iupacName "phosphonic acid".
- Q2341200 pubchem "25419".
- Q2341200 unii "813".
- Q2341200 type ChemicalSubstance.
- Q2341200 type Drug.
- Q2341200 type ChemicalObject.
- Q2341200 type Thing.
- Q2341200 type Q8386.
- Q2341200 comment "Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate.".
- Q2341200 label "Clodronic acid".
- Q2341200 depiction Clodronic_acid.png.