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- Q20707377 abstract "NPS-2143 (SB-262,470A) is a calcilytic drug which acts as an antagonist at the Calcium-sensing receptor (CaSR), and consequently stimulates release of parathyroid hormone. Calcilytic drugs have been researched as potential treatments for osteoporosis, and as the first such compound developed, NPS-2143 is still widely used in research into the CaSR receptor as well as design of newer calcilytic agents.".
- Q20707377 casNumber "324523-20-8".
- Q20707377 iupacName "2-chloro-6-[(2R)-3-([1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino)-2-hydroxypropoxy]benzonitrile".
- Q20707377 pubchem "6918446".
- Q20707377 thumbnail NPS-2143_structure.png?width=300.
- Q20707377 wikiPageWikiLink Q14860476.
- Q20707377 wikiPageWikiLink Q15321271.
- Q20707377 wikiPageWikiLink Q165328.
- Q20707377 wikiPageWikiLink Q193978.
- Q20707377 wikiPageWikiLink Q19903703.
- Q20707377 wikiPageWikiLink Q410943.
- Q20707377 casNumber "324523".
- Q20707377 iupacName "2".
- Q20707377 pubchem "6918446".
- Q20707377 type ChemicalSubstance.
- Q20707377 type Drug.
- Q20707377 type ChemicalObject.
- Q20707377 type Thing.
- Q20707377 type Q8386.
- Q20707377 comment "NPS-2143 (SB-262,470A) is a calcilytic drug which acts as an antagonist at the Calcium-sensing receptor (CaSR), and consequently stimulates release of parathyroid hormone. Calcilytic drugs have been researched as potential treatments for osteoporosis, and as the first such compound developed, NPS-2143 is still widely used in research into the CaSR receptor as well as design of newer calcilytic agents.".
- Q20707377 label "NPS-2143".
- Q20707377 depiction NPS-2143_structure.png.