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- Q19598411 subject Q7158320.
- Q19598411 subject Q7311092.
- Q19598411 subject Q8256076.
- Q19598411 subject Q8522216.
- Q19598411 subject Q8839994.
- Q19598411 abstract "Paroxypropione (INN) (brand names Frenantol, Frenormon, Hypophenon, Paroxon, Possipione, Profenone, numerous others; former developmental code name NSC-2834), also known as paroxypropiophenone (P.O.P.) or 4'-hydroxypropiophenone, is a synthetic, non-steroidal estrogen that has been used medically as an antigonadotropin in Spain and Italy. It is closely related structurally to p-hydroxybenzoic acid and parabens such as methylparaben, and also bears a close resemblance to diethylstilbestrol (which, in fact, produces paroxypropione as an active metabolite) and alkylphenols like nonylphenol, all of which are also estrogens. The drug possesses relatively low affinity for the estrogen receptor and must be given at high dosages to achieve significant estrogenic and antigonadotropic action, for instance, 0.8 to 1.6 g/day. Paroxypropione was first synthesized in 1902. Its antigonadotropic properties were discovered in 1951 and it entered clinical use shortly thereafter.Similarly to p-hydroxybenzoic acid, paroxypropione has been found to possess antioxidant activity.Paroxypropione is a precursor in the chemical synthesis of diethylstilbestrol and dienestrol.".
- Q19598411 atcPrefix "None".
- Q19598411 casNumber "70-70-2".
- Q19598411 iupacName "1-(4-Hydroxyphenyl)-1-propanone".
- Q19598411 pubchem "6271".
- Q19598411 thumbnail Paroxypropione.svg?width=300.
- Q19598411 wikiPageWikiLink Q133948.
- Q19598411 wikiPageWikiLink Q20707196.
- Q19598411 wikiPageWikiLink Q229970.
- Q19598411 wikiPageWikiLink Q229987.
- Q19598411 wikiPageWikiLink Q247994.
- Q19598411 wikiPageWikiLink Q273499.
- Q19598411 wikiPageWikiLink Q277954.
- Q19598411 wikiPageWikiLink Q29.
- Q19598411 wikiPageWikiLink Q38.
- Q19598411 wikiPageWikiLink Q410780.
- Q19598411 wikiPageWikiLink Q416496.
- Q19598411 wikiPageWikiLink Q416769.
- Q19598411 wikiPageWikiLink Q419147.
- Q19598411 wikiPageWikiLink Q423989.
- Q19598411 wikiPageWikiLink Q4677569.
- Q19598411 wikiPageWikiLink Q4774757.
- Q19598411 wikiPageWikiLink Q5274949.
- Q19598411 wikiPageWikiLink Q7158320.
- Q19598411 wikiPageWikiLink Q7311092.
- Q19598411 wikiPageWikiLink Q824258.
- Q19598411 wikiPageWikiLink Q8256076.
- Q19598411 wikiPageWikiLink Q8522216.
- Q19598411 wikiPageWikiLink Q8839994.
- Q19598411 wikiPageWikiLink Q899107.
- Q19598411 atcPrefix "None".
- Q19598411 casNumber "70".
- Q19598411 iupacName "1".
- Q19598411 pubchem "6271".
- Q19598411 type ChemicalSubstance.
- Q19598411 type Drug.
- Q19598411 type ChemicalObject.
- Q19598411 type Thing.
- Q19598411 type Q8386.
- Q19598411 comment "Paroxypropione (INN) (brand names Frenantol, Frenormon, Hypophenon, Paroxon, Possipione, Profenone, numerous others; former developmental code name NSC-2834), also known as paroxypropiophenone (P.O.P.) or 4'-hydroxypropiophenone, is a synthetic, non-steroidal estrogen that has been used medically as an antigonadotropin in Spain and Italy.".
- Q19598411 label "Paroxypropione".
- Q19598411 depiction Paroxypropione.svg.